Nonischemic cardiomyopathy is defined as disease of the myocardium associated with mechanical or electrical dysfunction exhibiting inappropriate ventricular hypertrophy or dilatation. The causes are numerous, but an increasing number of nonischemic disorders are being recognized as genetic in cause.
Ischemic cardiomyopathy is most common. It occurs when the heart is damaged from heart attacks due to coronary artery disease. Non-ischemic cardiomyopathy is less common. It includes types of cardiomyopathy that are not related to coronary artery disease.
Dilated cardiomyopathy, also sometimes referred to as dilated, non-ischemic cardiomyopathy, is a type of heart muscle disease that causes the left ventricle of the heart to stretch abnormally. This prevents your heart from pumping blood effectively.
Many epidemiological and clinical studies simply classify patients as having NICM if heart failure is present but there is no clinical or electrocardiographic evidence of coronary disease.
What causes cardiomyopathy?Autoimmune diseases, such as connective tissue diseases.Conditions that damage the heart, such as high cholesterol diseases, hemochromatosis or sarcoidosis.Endocrine conditions, such as diabetes or thyroid disease.Family history of heart failure, cardiomyopathy or sudden cardiac arrest.More items...•Apr 28, 2021
Medical Definition of nonischemic : not marked by or resulting from ischemia nonischemic tissue.
Although the long term prognosis of patients with dilated cardiomyopathy (DCM) remains poor, approximately 25% of DCM patients with recent onset of heart failure (< 6 months) have a relatively benign clinical course with a spontaneously improvement in symptoms and partial, or in some cases complete, recovery of left ...
Ischemic cardiomyopathy accounts for about half of these patients, but in several large clinical trials the prevalence of potentially reversible nonischemic cardiomyopathy is also significant, ranging from 20% to 50%.