icd 10 cm code for chronic myeloid leukemia bcr/abl positive, in remission

by Gaston Feest MD 5 min read

Chronic myeloid leukemia, BCR/ABL-positive, in remission
C92. 11 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM C92. 11 became effective on October 1, 2021.

What is the ICD 10 code for BCR positive chronic myeloid leukemia?

2018/2019 ICD-10-CM Diagnosis Code C92.10. Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission. 2016 2017 2018 2019 Billable/Specific Code.

What is the ICD 10 code for leukemia in remission?

ICD-10-CM Code C92.11 Chronic myeloid leukemia, BCR/ABL-positive, in remission. C92.11 is a billable ICD code used to specify a diagnosis of chronic myeloid leukemia, BCR/ABL-positive, in remission. A 'billable code' is detailed enough to be used to specify a medical diagnosis.

What is the hallmark of chronic myeloid leukemia (CML)?

Chronic leukemia in which myeloid progenitor cells predominate; the hallmark of cml, the philadelphia chromosome, is a reciprocal translocation between chromosomes 9 and 22 which activates the proto- oncogene c-abl. Clonal hematopoetic disorder caused by an acquired genetic defect in pluripotent stem cells.

What is the ICD 10 code for chronic myeloid leukodystrophy?

C92.10 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Short description: Chronic myeloid leuk, BCR/ABL-positive, not achieve remis The 2020 edition of ICD-10-CM C92.10 became effective on October 1,...

What is chronic myeloid leukemia BCR-ABL positive?

Definition. Chronic myeloid leukemia (CML), BCR-ABL1-positive, is a myeloproliferative neoplasm (MPN) in which granulocytes are the major proliferative component. It arises in a hematopoietic stem cell and is characterized by the chromosomal translocation t(9;22)(q34.

What is the ICD-10-CM code for chronic myeloid leukemia?

ICD-10-CM Code for Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission C92. 10.

What is remission in CML?

Treatment-free remission (TFR) is now an emerging treatment goal for many patients with CML who have achieved a deep and stable response to treatment. Treatment-free remission is achieved when a patient who has discontinued TKI therapy maintains a deep molecular response (DMR) and does not need to restart treatment.

What is CML and BCR-ABL?

The BCR-ABL gene shows up in patients with certain types of leukemia, a cancer of the bone marrow and white blood cells. BCR-ABL is found in almost all patients with a type of leukemia called chronic myeloid leukemia (CML). Another name for CML is chronic myelogenous leukemia. Both names refer to the same disease.

What is the ICD-10 code for leukemia?

C95. 9 - Leukemia, unspecified. ICD-10-CM.

What is the ICD-10 code for MDS?

9.

How do you know if CML is in remission?

Your doctor will use blood test results to figure out which remission category you're in. They'll refer to these different groups as "responses." Complete hematologic response. It means your blood cell count is back to normal and tests don't show any abnormal white blood cells.

Can CML come back after remission?

CML can potentially come back after going into remission. This is known as relapse. If you obtain remission after treatment with TKIs, your doctor will likely advise you to continue TKI therapy for at least two years to lower your risk of relapse.

What is free remission?

Abstract. In CML, treatment-free remission (TFR) refers to having a stable deep molecular response without the need for ongoing tyrosine kinase inhibitor treatment.

Which targeted therapy will be use if BCR-ABL mutation is positive?

Imatinib. Imatinib (Gleevec) was the first drug to specifically target the BCR-ABL tyrosine kinase protein.

What is BCR-ABL negative?

Atypical chronic myeloid leukemia (aCML), BCR-ABL1 negative is a rare myelodysplastic syndrome/myeloproliferative neoplasm for which no current standard of care exists. The blood smear of patients with aCML showed prominent immature granulocytosis, and granulocytic dysplasia.

What is meant by BCR?

The benefit-cost ratio (BCR) is an indicator showing the relationship between the relative costs and benefits of a proposed project, expressed in monetary or qualitative terms. If a project has a BCR greater than 1.0, the project is expected to deliver a positive net present value to a firm and its investors.

What is the code for a primary malignant neoplasm?

A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere.

What is the hallmark of a CML?

A slowly progressing disease in which too many white blood cells are made in the bone marrow. Chronic leukemia in which myeloid progenitor cells predominate; the hallmark of cml, the philadelphia chromosome, is a reciprocal translocation between chromosomes 9 and 22 which activates the proto- oncogene c-abl.

What is a BCR fusion?

A chronic myeloproliferative neoplasm characterized by the expression of the bcr -abl1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.

How long does leukemia last?

The condition progresses from a stable, more indolent, chronic phase (leukemia, myeloid, chronic phase) lasting up to 7 years, to an advanced phase composed of an accelerated phase (leukemia, myeloid, accelerated phase) and blast crisis. leukemia is cancer of the white blood cells.

What is a type 1 exclude note?

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as C92.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

What chapter is neoplasms classified in?

All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology] Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, ...

Does CML cause a chromosome change?

In chronic myeloid leukemia (cml), there are too many granulocytes, a type of white blood cell.most people with cml have a gene mutation (change) called the philadelphia chromosome.sometimes cml does not cause any symptoms.

What is CML in medical terms?

Chronic myelogenous (or myeloid or myelocytic) leukemia (CML), also known as chronic granulocytic leukemia (CGL), is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes (neutrophils, eosinophils and basophils) and their precursors is found. It is a type of myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome. CML is now largely treated with targeted drugs called tyrosine kinase inhibitors (TKIs) which have led to dramatically improved long-term survival rates since the introduction of the first such agent in 2001. These drugs have revolutionized treatment of this disease and allow most patients to have a good quality of life when compared to the former chemotherapy drugs. In Western countries it accounts for 15-20% of all adult leukemias and 14% of leukemias overall (including the pediatric population).

What is the treatment for CML?

CML is now largely treated with targeted drugs called tyrosine kinase inhibitors (TKIs) which have led to dramatically improved long-term survival rates since the introduction of the first such agent in 2001.

What is CML stem cell?

CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes (neutrophils, eosinophils and basophils) and their precursors is found . It is a type of myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome.

What is CML in medical terms?

Chronic myelogenous (or myeloid or myelocytic) leukemia (CML), also known as chronic granulocytic leukemia (CGL), is a cancer of the white blood cells. It is a form of leukemia characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood. CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes (neutrophils, eosinophils and basophils) and their precursors is found. It is a type of myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome. CML is now largely treated with targeted drugs called tyrosine kinase inhibitors (TKIs) which have led to dramatically improved long-term survival rates since the introduction of the first such agent in 2001. These drugs have revolutionized treatment of this disease and allow most patients to have a good quality of life when compared to the former chemotherapy drugs. In Western countries it accounts for 15-20% of all adult leukemias and 14% of leukemias overall (including the pediatric population).

What is the treatment for CML?

CML is now largely treated with targeted drugs called tyrosine kinase inhibitors (TKIs) which have led to dramatically improved long-term survival rates since the introduction of the first such agent in 2001.

What is CML stem cell?

CML is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes (neutrophils, eosinophils and basophils) and their precursors is found . It is a type of myeloproliferative disease associated with a characteristic chromosomal translocation called the Philadelphia chromosome.