1 – Benign Prostatic Hyperplasia with Lower Urinary Tract Symptoms.
Listen to pronunciation. (beh-NINE prah-STA-tik hy-PER-troh-fee) A benign (not cancer) condition in which an overgrowth of prostate tissue pushes against the urethra and the bladder, blocking the flow of urine. Also called benign prostatic hyperplasia and BPH.
Benign prostatic hyperplasia—also called BPH—is a condition in men in which the prostate gland is enlarged and not cancerous. Benign prostatic hyperplasia is also called benign prostatic hypertrophy or benign prostatic obstruction. The prostate goes through two main growth periods as a man ages.
Overview. Benign prostatic hyperplasia (BPH) — also called prostate gland enlargement — is a common condition as men get older. An enlarged prostate gland can cause uncomfortable urinary symptoms, such as blocking the flow of urine out of the bladder. It can also cause bladder, urinary tract or kidney problems.
BPH arises as a result of the loss of homeostasis between cellular proliferation and cell death, resulting in an imbalance favoring cellular proliferation. This results in increased numbers of epithelial and stromal cells in the periurethral area of the prostate and can be seen histopathologically[5].
An enlarged median lobe is important in the setting of BPH and should be considered in treatment planning. Medication is not as effective for men with moderate-to-severe MLE or IPP compared to those without and is associated with poorer outcomes.
Hyperplasia refers to the process where cells in an organ or tissue increase in number, so its like hiring a bigger pack of lumberjacks. Hypertrophy is when these cells in an organ or tissue increase in size, like if the lumberjack gets really tough so that she can cut down twice as many trees.
DiagnosisDigital rectal exam. The doctor inserts a finger into the rectum to check your prostate for enlargement.Urine test. Analyzing a sample of your urine can help rule out an infection or other conditions that can cause similar symptoms.Blood test. ... Prostate-specific antigen (PSA) blood test.
Hypertrophy refers to an increase in the size of individual muscle fibers, whereas hyperplasia refers to an increase in the number of muscle fibers.
Symptoms and Causes Therefore, you may develop early symptoms of BPH: Slowness or dribbling of your urinary stream. Hesitancy or difficulty starting to urinate. Frequent urination.
The gold standard for the management of BPH is surgical treatment by transurethral resection of the prostate (TURP). However, in older adults, medical therapy is preferred to surgical intervention when possible.
An enlarged prostate means the gland has grown bigger. Prostate enlargement happens to almost all men as they get older. An enlarged prostate is often called benign prostatic hyperplasia (BPH). It is not cancer, and it does not raise your risk for prostate cancer.
The gold standard for the management of BPH is surgical treatment by transurethral resection of the prostate (TURP). However, in older adults, medical therapy is preferred to surgical intervention when possible.
What Are the Warning Signs and Symptoms of BPH?weak urine flow;difficulty starting urination;dribbling of urine, especially after urinating;a sense of not fully emptying the bladder;leaking of urine;more frequent urination and a strong and sudden desire to urinate, especially at night; and.blood in the urine.
Alpha blockers. These medications relax bladder neck muscles and muscle fibers in the prostate, making urination easier. Alpha blockers — which include alfuzosin (Uroxatral), doxazosin (Cardura), tamsulosin (Flomax) and silodosin (Rapaflo) — usually work quickly in men with relatively small prostates.
The increase in prostate volume was measurable in each 10-year age group and doubled from 5.5 ml in 40–49 years to 11.1 ml in 70–80 years.