icd 10 code for bernard-soulier syndrome

What is the ICD 10 code for Bernard-Horner syndrome?

Diagnosis Index entries containing back-references to G90.2: Bernard-Horner syndrome G90.2 Claude Bernard-Horner syndrome G90.2 Dystrophy, dystrophia sympathetic (reflex) - see Syndrome, pain, complex regional I cervical G90.2 Horner (-Claude Bernard) G90.2 Syndrome - see also Disease cervical (root) M53.1 ICD-10-CM Diagnosis Code M53.1

What is the differential diagnosis for Bernard-Soulier syndrome (BSS)?

The differential diagnosis for Bernard–Soulier syndrome includes both Glanzmann thrombasthenia and pediatric Von Willebrand disease. BSS platelets do not aggregate to ristocetin, and this defect is not corrected by the addition of normal plasma, distinguishing it from von Willebrand disease.

What is the ICD 10 code for Bartter's syndrome?

Bartter's syndrome. E26.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2019 edition of ICD-10-CM E26.81 became effective on October 1, 2018.

What are the symptoms of Bernard-Soulier syndrome?

Bernard–Soulier syndrome often presents as a bleeding disorder with symptoms of: Perioperative (and postoperative) bleeding. Bleeding gums. Bruising. Epistaxis (nosebleeds) Abnormal bleeding (from small injuries)

What is Bernard-Soulier disease?

Bernard-Soulier syndrome (BSS) is a rare inherited disorder of blood clotting (coagulation) characterized by unusually large platelets, low platelet count (thrombocytopenia) and prolonged bleeding time (difficulty in clotting).

What does it mean when you have giant platelets?

Giant platelet disorders, also known as macrothrombocytopenia, are rare disorders featuring abnormally large platelets, thrombocytopenia and a tendency to bleeding. Giant platelets cannot stick adequately to an injured blood vessel walls, resulting in abnormal bleeding when injured.

Which characteristic of Bernard-Soulier syndrome helps distinguish it from von Willebrand disease?

Low to absent response to ristocetin is a reliable indicator for the diagnosis of BSS (rules out vWD). Flow cytometry is used to confirm the diagnosis.

What causes large giant platelets?

The giant platelets cause comes from a genetic abnormality. The gene responsible for the syndrome has been mapped to the short (p) arm of chromosome 17. If both parents carry the gene for Bernard-Soulier syndrome and transmit that gene to the child, the child will be born with the disorder.

What is the difference between large platelets and giant platelets?

Large platelets have a diameter greater than 4 microns. Giant platelets have a diameter greater than 7 microns (larger than a normal red blood cell). Large platelets can be seen when platelet turnover is increased (as in immune thrombocytopenic purpura).

How do you treat Bernard-Soulier syndrome?

Management of Bernard-Soulier syndrome Care of patients with Bernard-Soulier syndrome (BSS) is generally supportive. In most cases, no medications are needed. Bleeding episodes may require nonspecific treatment, such as desmopressin acetate (DDAVP) or antifibrinolytic agents.

What do Bernard-Soulier syndrome and Glanzmann's thrombasthenia have in common?

Glanzmann's thrombasthenia and Bernard-Soulier syndrome are platelet receptor defects that result in abnormal platelet adhesion and/or aggregation.

Why are platelets low in Bernard-Soulier syndrome?

The large platelets and low platelet count in BSS are seemingly due to the absence of GPIbα and the filamin A binding site that links the GPIb-IX-V complex to the platelet membrane skeleton.

Which platelet aggregation result would be characteristic for patients with Bernard-Soulier syndrome?

Bernard–Soulier syndrome (BSS) is an autosomal recessive platelet disorder characterized by thrombocytopenia, the presence of giant platelets, and defective ristocetin-induced platelet agglutination.

Which is the most common cause of acquired platelet dysfunction?

Acquired platelet dysfunction, which is common, may result from aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), or systemic disorders.

What is Glanzmann's thrombasthenia?

General Discussion. Glanzmann thrombasthenia (GT) is a rare inherited blood clotting (coagulation) disorder characterized by the impaired function of specialized cells (platelets) that are essential for proper blood clotting. Symptoms of this disorder usually include abnormal bleeding, which may be severe.