Enterocolitis due to Clostridium difficile, recurrent. 2018 - New Code 2019 Billable/Specific Code. A04.71 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
Clostridium Difficile Enterocolitis (C. diff) is a diagnosis that coders see a lot these days.
Clostridium perfringens [C. perfringens] as the cause of diseases classified elsewhere Clostridium perfringens causing diseases classd elswhr; Clostridium perfringens infection; Infection due to clostridium perfringens ICD-10-CM Diagnosis Code K55.3
This is the American ICD-10-CM version of A04.7 - other international versions of ICD-10 A04.7 may differ. carrier or suspected carrier of infectious disease ( Z22.-) infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium ( O98.-) code to identify resistance to antimicrobial drugs ( Z16.-)
Possible relevant ICD-10 codes for DIFICIDCodeDiagnosisA04.71Enterocolitis due to Clostridium difficile, recurrentA04.72Enterocolitis due to Clostridium difficile, not specified as recurrent
7.
C. diff is a spore-forming, Gram-positive anaerobic bacillus that produces two exotoxins: toxin A and toxin B. It is a common cause of antibiotic-associated diarrhea (AAD) and accounts for 15 to 25% of all episodes of AAD.
C. difficile infection is the most common cause of diarrhea in people who develop diarrheal symptoms while hospitalized. C. difficile toxin is detected in the stools of up to 20-30% of those with antibiotic-associated diarrhea and greater than 95% of those with pseudomembranous colitis.
The International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9) code used in this study was 008.45, "intestinal infection due to Clostridium difficile," and is the only ICD-9 code related to CDAD.
Clostridioides difficile (klos-TRID-e-oi-deez dif-uh-SEEL) is a bacterium that causes an infection of the large intestine (colon). Symptoms can range from diarrhea to life-threatening damage to the colon.
Stool Test The simplest way to detect C. difficile is through a stool test, in which you provide a sample in a sterile container given to you at your doctor's office or a lab. A pathologist, a doctor who studies diseases in a laboratory, determines whether the sample has signs of C. difficile.
Difficile Antigen and Toxins A and B. Clostridium difficile is a normal bacteria found in the intestine. However, after treatment with broad-spectrum antibiotics, the bacteria can become very abundant in the intestine and cause diarrhea that is often severe and accompanied by fever, pain and other complications.
Clostridium difficile PCR is designed to amplify 2 different genes that are specific to toxigenic strains of C difficile: tcdB, which encodes for toxin B, and tcdC, which encodes for a toxin regulatory pathway.
difficile toxins that are involved in disease. Toxin A (encoded by the tcdA gene) is an enterotoxin that causes fluid accumulation in the bowel. Toxin B (encoded by the tcdB gene) is cytopathic to (causes distortion of) cells when cultured in the laboratory. The tcdC gene regulates toxin A and B production.
Only toxin-producing C diff strains cause disease and toxins A and B (encoded by the tcdA and tcdB genes) appear to play important roles. The toxins are pro-inflammatory enterotoxins, but toxin B is a more potent cytotoxin.
Repeat stool testing for test of cure is NOT recommended. Up to 50% of patients have positive C diff PCR for as long as six weeks after the completion of therapy. Therefore, signs and symptoms rather than repeat testing should be used to assess whether a patient has responded to therapy for C.
ICD-10 code R19. 7 for Diarrhea, unspecified is a medical classification as listed by WHO under the range - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified .
Pseudomembranous colitis occurs when certain bacteria — usually C. difficile — rapidly outgrow other bacteria that normally keep them in check. Certain toxins produced by C. difficile, which are usually present in only tiny amounts, rise to levels high enough to damage the colon.
ICD-10 code: A04. 72 Enterocolitis due to Clostridium difficile with toxic megacolon, without other organ complications.
Administer ZINPLAVA during antibacterial drug treatment for CDI. The recommended dose of ZINPLAVA is a single dose of 10 mg/kg administered as an intravenous infusion over 60 minutes. The safety and efficacy of repeat administration of ZINPLAVA in patients with CDI have not been studied.
The 2021 edition of ICD-10-CM A04.7 became effective on October 1, 2020.
The 2022 edition of ICD-10-CM A04.7 became effective on October 1, 2021.
If the GDH Antigen is detected and the Toxin A and B are not detected or the GDH Antigen is not detected and the Toxin A and B are detected, Clostridium difficile Toxin B, Qualitative, Real-Time PCR will be performed at an additional charge (CPT code (s): 87493).
Collect fresh stool in sterile, leak-proof container without media, preservative, or metal ion. For patients requiring the use of diapers, first line the diaper with clean plastic to prevent absorption. Then transfer 5 grams or 5 mL of the stool specimen from the plastic lined diaper to the sterile container. Do not submit the diaper itself.
Formed stool • Stool submitted in transport media or swab • Rectal swab • Unfrozen stool >72 hours old • Received room temperature
Collect fresh stool in sterile, leak-proof container without media, preservative, or metal ion. For patients requiring the use of diapers, first line the diaper with clean plastic to prevent absorption. Then transfer 5 grams or 5 mL of the stool specimen from the plastic lined diaper to the sterile container.
The ELISA for toxin is known to have a super high rate of false negative tests.. Up to 75% of the time you can get a negative test for this even when the C. Diff is present
2. Diarrhea secondary to acute gastroenteritis with negative Clostridium
If it were established as non-toxogenic however, the patient would be expected to be 1) asymptomatic, 2) not be receiving treatment and 3) Not meeting reportability under the UHDDS.
If the patient is having symptoms the odds are significantly reduced that they are actually nontoxigenic unless there is a named alternative cause to explain the diarrhea some where in the record.