icd 10 code for cardiolipinigg ab

Full Answer

What is cardiolipin AB IgG?

A cardiolipin antibodies test looks for a certain kind of antibody in your blood. The antibodies are IgG (immunoglobulin G), IgA (immunoglobulin A), and IgM (immunoglobulin M). They are antibodies that form in response to cardiolipins. Cardiolipin is a phospholipid, or a kind of fat in the blood.

What does high cardiolipin AB IgG mean?

- Moderately or very high levels of anticardiolipin antibodies that persist for 12 weeks or more indicate a continued presence of these autoantibodies and an increased risk of abnormal clots and miscarriages.

What is cardiolipin AB test?

A cardiolipin antibodies test looks for a certain kind of antibody in your blood. An antibody is a substance in your blood that helps fight off infection. The antibodies attack cardiolipins by mistake. Cardiolipin is a phospholipid, or a kind of fat in the blood that is important for blood clotting.

What is the ICD-10 code for antiphospholipid antibody?

ICD-10 code D68. 61 for Antiphospholipid syndrome is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .

What is cardiolipin AB IgA IgG IgM?

The cardiolipin antibodies blood test, IgA, IgG, and IgM is used to help investigate inappropriate blood clot formation, to help determine the cause of recurrent miscarriage, or as part of an evaluation for antiphospholipid syndrome or sometimes other autoimmune diseases.

What is Anticardiolipin AB IgM QN?

Anticardiolipins are antibodies produced by the immune system against the platelet membrane phospholipids responsible for the coagulation of blood clots.

What is the normal range for cardiolipin AB IgG?

IgG Cardiolipin antibodies: Negative : <10.0 GPL U/ml. Weak Positive : 10.0-40.0 GPL U/ml. Positive: >40 GPL U/ml.

What is cardiolipin IGA antibody?

Cardiolipin antibodies are the most common antiphospholipid antibody, a group of autoantibodies associated with excessive clotting and autoimmune diseases, such as lupus. They are frequently detected with other antiphospholipid antibodies, such as lupus anticoagulant and anti-beta-2 glycoprotein 1.

What is the ICD-10 code for anticardiolipin antibodies?

Antiphospholipid antibody with hemorrhagic disorder D68. 312 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D68. 312 became effective on October 1, 2021.

What is antiphospholipid antibody positive?

Antiphospholipid (AN-te-fos-fo-LIP-id) syndrome is a condition in which the immune system mistakenly creates antibodies that attack tissues in the body. These antibodies can cause blood clots to form in arteries and veins. Blood clots can form in the legs, lungs and other organs, such as the kidneys and spleen.

What does positive anticardiolipin antibodies mean?

The presence of an antiphospholipid antibody such as the lupus anticoagulant and anticardiolipin antibody in an individual is associated with a predisposition for blood clots. Blood clots can form anywhere in the body and can lead to stroke, gangrene, heart attack, and other serious complications.

Clinical Significance

Cardiolipin Antibodies (IgA, IgG, IgM) - Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly systemic lupus erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion.

Preferred Specimen (s)

1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube

Test Includes

Anticardiolipin antibodies, IgA, quantitative; anticardiolipin antibodies, IgG, quantitative; anticardiolipin antibodies, IgM, quantitative

Expected Turnaround Time

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Limitations

ACA can often be observed during the convalescent phase of acute bacterial and viral infections and in individuals with syphilis. These infection-induced antibodies are usually transient and are not associated with an increased risk of clinical complications.

Methodology

Enzyme-linked immunosorbent assay (ELISA) detecting isotype-specific ACA binding to a microtiter plate coated with purified cardiolipin antigen

Additional Information

Individuals with the antiphospholipid antibody syndrome (APS) have an increased risk for stroke, myocardial infarction, venous thrombosis, thromboembolism, thrombocytopenia, and/or recurrent miscarriages.

Footnotes

1. Wilson WA, Gharavi AE, Koike T, et al. International Consensus Statement on Preliminary Classification Criteria for Definite Antiphospholipid Syndrome: Report of an International Workshop. Arthritis Rheum. 1999; 42 (7):1309-1311. PubMed 10403256