The appropriate ICD-9-CM code is 233.1 (CIN III/CIS/Severe Dysplasia). The appropriate ICD-10-CM code is D06.
What is CIN2? Abnormal cells in the cervix are known as CIN (Cervical Intraepithelial Neoplasia). There are three grades of CIN. The grades describe how far the abnormal cells have gone into the surface layer of the cervix. CIN2 means that abnormal cells have been found in two thirds of the thickness of the skin.
One explanation for the lower rate of progression of CIN 2 compared with CIN 3 is that CIN 2 is more likely to be caused by oncogenic HPV subtypes 31, 33, 35, 39, 45, 51, 52, and 58, which have a weaker association with development of cancer than the more highly oncogenic subtypes HPV 16 and 18, which are commonly ...
CIN2 – indicates moderate changes; affecting two-thirds of the thickness of the surface layer of the cervix. CIN3 – indicates more severe changes (not cancer); affecting the full thickness of the surface layer of the cervix. Even with CIN2 or CIN3 grade changes, the cell changes are unlikely to be cancer.
CIN2 and CIN3 are always caused by high-risk HPV infections. The typical treatment procedure for CIN2 or CIN3 involves removing a cone-shaped piece of the cervix, called a LEEP or a cone.
INTRODUCTION. Cervical intraepithelial neoplasia (CIN) is a premalignant condition of the uterine cervix. The ectocervix (surface of the cervix that is visualized on vaginal speculum examination) is covered in squamous epithelium, and the endocervix, including the cervical canal, is covered with glandular epithelium.
HSIL ~ High-grade squamous intraepithelial lesion This diagnosis means the cells appear very different from normal cells. These precancerous lesions are more severe than with LSIL, but involve cells on the surface of the cervix. They may also be called moderate or severe dysplasia, or CIN 2 or 3.
How is CIN 2 & 3 managed? Given the lower rates of spontaneous regression and higher rates of progression, it is recommended that most women with CIN 2 or CIN 3 undergo treatment. Both ablative and excisional procedures are used, with similar efficacy rates (>90% cure) in properly selected patients.
Human Papillomavirus Infection Not everyone who gets HPV will experience CIN, though. Experts say the immune system is well suited to clearing HPV infections without any external intervention. CIN is usually caused by HPV, a sexually transmitted infection.
CIN 3 means the full thickness of the cervical surface layer is affected by abnormal cells. CIN 3 is also called carcinoma-in-situ. This sounds like cancer, but CIN 3 is not cervical cancer. Cancer develops when the deeper layers of the cervix are affected by abnormal cells.
In a meta-analysis of 36 studies involving 3,160 women with CIN2 who were actively monitored for at least 3 months, 50% of the lesions regressed spontaneously, 32% persisted, and just under one in five (18%) progressed to CIN3 or worse within 2 years.
CGIN is usually classified as low grade (mild) or high grade (severe). High grade CGIN is the equivalent of CIN3. CGIN can be multi-focal – this means that more than one area is affected at one time, with normal tissue lying between them.
The 2022 edition of ICD-10-CM D07.2 became effective on October 1, 2021.
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology] Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, ...