icd 10 code for cosyntropin stimulation test

by Dr. Lloyd Willms II 6 min read

Unspecified adrenocortical insufficiency
E27. 40 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM E27.

Full Answer

What is the HCPCS code for cosyntropin?

HCPCS Code J0834. Injection, cosyntropin, 0.25 mg. Drugs administered other than oral method, chemotherapy drugs. J0834 is a valid 2019 HCPCS code for Injection, cosyntropin, 0.25 mg or just “Inj., cosyntropin, 0.25 mg” for short, used in Medical care.

What is a cosyntropin test?

HelpHelp /Home /ACTH Stimulation Test (Cosyntropin) ACTH Stimulation Test (Cosyntropin) Purpose: Evaluation of possible primary or secondary adrenal insufficiency, as well as disorders of adrenal steroid biosynthesis, such as congenital adrenal hyperplasia (CAH).1,2

What is the ACTH stimulation test (cosyntropin)?

ACTH Stimulation Test (Cosyntropin) 1 (1) ACTH deficiency is suspected. Atrophy of the adrenal cortex due to ACTH deficiency may result in... 2 (2) Disorder of steroid biosynthesis (CAH) is suspected. 3 (3) Primary adrenal insufficiency is suspected. 4 (4) Cortical suppression by chronic corticosteroid administration is suspected.

What is the ICD 10 code for neurostimulator?

Presence of neurostimulator Z96.82 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2021 edition of ICD-10-CM Z96.82 became effective on October 1, 2020. This is the American ICD-10-CM version of Z96.82 - other international versions of ...

image

What is a Cosyntropin stimulation test?

Cosyntropin stimulation test (CST) is a frequently used dynamic test for the evaluation of the hypothalamus-pituitary-adrenal (HPA) axis in patients suspected of adrenal insufficiency (AI).

What diagnosis is Z13 29?

ICD-10 code Z13. 29 for Encounter for screening for other suspected endocrine disorder is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .

What is R68 89 diagnosis code?

ICD-10 code R68. 89 for Other general symptoms and signs is a medical classification as listed by WHO under the range - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified .

What is the ICD-10 code for adrenal insufficiency?

ICD-10 code E27. 40 for Unspecified adrenocortical insufficiency is a medical classification as listed by WHO under the range - Endocrine, nutritional and metabolic diseases .

What is the ICD-10 code for annual physical exam?

Z00.00ICD-10 Code for Encounter for general adult medical examination without abnormal findings- Z00. 00- Codify by AAPC.

What ICD-10 covers cortisol levels?

Unspecified adrenocortical insufficiency E27. 40 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM E27. 40 became effective on October 1, 2021.

Is R68 89 a billable code?

R68. 89 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM R68. 89 became effective on October 1, 2021.

What is Z00 01?

ICD-10 code Z00. 01 for Encounter for general adult medical examination with abnormal findings is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .

What ICD-10 code covers CBC?

NCD 190.15 In some patients presenting with certain signs, symptoms or diseases, a single CBC may be appropriate.

How does ACTH Stim test work?

Your blood is drawn. You then receive a shot (injection) of ACTH, usually into the muscle in your shoulder. The ACTH may be a man-made (synthetic) form. After either 30 minutes or 60 minutes, or both, depending on how much ACTH you receive, your blood is drawn again.

What is the ICD-10 code for ASHD?

ICD-10 Code for Atherosclerotic heart disease of native coronary artery without angina pectoris- I25. 10- Codify by AAPC.

What is ACTH deficiency?

General Discussion. ACTH deficiency arises as a result of decreased or absent production of adrenocorticotropic hormone (ACTH) by the pituitary gland. A decline in the concentration of ACTH in the blood leads to a reduction in the secretion of adrenal hormones, resulting in adrenal insufficiency (hypoadrenalism).

When is the ACTH test performed?

Although it may make more physiologic sense to perform the test during the nadir of endogenous ACTH production (around midnight) it is usually performed at 8:00-9:00 AM for ease of collection and comparison to normative data that was collected during that time-frame.

Can cortisol interfere with ACTH?

Prior administration of estrogens, spironolactone, cortisone, and hydrocortisone (cortisol) can all interfere with the ACTH stimulation test by causing abnormally high baseline cortisol levels.

Does ACTH cause adrenal cortex atrophy?

Atrophy of the adrenal cortex due to ACTH deficiency may result in the lack of a significant cortisol response to single-pulse ACTH administration; the aldosterone response usually remains normal due to its synthesis in the zona glomerulosa, which is orchestrated by the renin-angiotensin system, not ACTH.

HCPCS Modifiers

In HCPCS Level II, modifiers are composed of two alpha or alphanumeric characters.

See also

1 Two-digit numeric codes are Level I code modifiers copyrighted© by the American Medical Association's Current Procedural Terminology (CPT).

image

Purpose

Pharmacology

  • Rationale: Cosyntropin, (ACTH 1-24), consists of the first 24 amino acids of the N-terminal portion of the intact native ACTH molecule (ACTH 1-36). This portion comprises the biologically active region of intact ACTH and is less allergenic than other forms of ACTH. It acts rapidly when bound to the melanocortin-2 receptor (MC2R) of the adrenal cortex initiating synthesis and release of c…
See more on labcorp.com

Clinical significance

  • (1) ACTH deficiency is suspected. Atrophy of the adrenal cortex due to ACTH deficiency may result in the lack of a significant cortisol response to single-pulse ACTH administration; the aldosterone response usually remains normal due to its synthesis in the zona glomerulosa, which is orchestrated by the renin-angiotensin system, not ACTH. Repeated ACTH stimulation may be …
See more on labcorp.com

Diagnosis

  • Metyrapone and insulin tolerance tests (ITT) have been the standards for evaluation of the hypothalamic-pituitary-adrenal axis, although a low-dose (1 μg of cosyntropin) can be considered instead of the ITT.6-12 (2) Disorder of steroid biosynthesis (CAH) is suspected. A baseline and 60-minute poststimulation CAH Comprehensive Screen (androstenedion...
See more on labcorp.com

Contraindications

  • (3) Primary adrenal insufficiency is suspected. If in an adrenal insufficiency crisis stimulation testing can be delayed until patient stabilization although usually an ACTH level and cortisol measurement can be drawn before hydrocortisone administration. (4) Cortical suppression by chronic corticosteroid administration is suspected. If corticosteroid had been recently administe…
See more on labcorp.com

Results

  • Interpretation: A rise from the baseline of at least 7 μg/dL to 10 μg/dL of cortisol, reaching at least 18 μg/dL at 60 minutes post stimulation effectively rules out primary adrenal insufficiency and suggests that adrenal suppression is minimal. A blunted or absent response suggests some level of secondary adrenal insufficiency (cortical atrophy or significant suppression.) If a subnormal r…
See more on labcorp.com