Elevated Alkaline Phosphatase
What Causes Elevated Alkaline Phosphatase?
High alkaline phosphatase levels in the liver can indicate:
Elevated alkaline phosphatase describes the situation where the levels of alkaline phosphatase exceed the reference range. It can be associated with certain medical conditions or syndromes (e.g., hyperphosphatasia with mental retardation syndrome, HPMRS)
R74.8 is a billable ICD code used to specify a diagnosis of abnormal levels of other serum enzymes. A 'billable code' is detailed enough to be used to specify a medical diagnosis.
FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)
R74.8 is a billable diagnosis code used to specify a medical diagnosis of abnormal levels of other serum enzymes. The code R74.8 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.
A genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. Clinical manifestations include severe skeletal defects resembling vitamin d-resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes. (from Dorland, 27th ed)
The 2022 edition of ICD-10-CM E83.39 became effective on October 1, 2021.