icd 10 code for elevated factor 8

What is the ICD 10 code for factor VIII deficiency?

Hereditary factor VIII deficiency 1 D66 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 2 The 2019 edition of ICD-10-CM D66 became effective on October 1, 2018. 3 This is the American ICD-10-CM version of D66 - other international versions of ICD-10 D66 may differ.

What does a high factor 8 mean?

Factor VIII is an acute phase reactant and can be elevated in a number of clinical conditions. This can affect the accuracy of the test in diagnosing hemophilia. Factor VIII levels should not be used to determine the carrier status of females.

What is the ICD 10 code for elevated liver enzymes?

Diagnosis Index entries containing back-references to R74.8: Abnormal, abnormality, abnormalities - see also Anomaly serum level (of) enzymes R74.9 ICD-10-CM Diagnosis Code R74.9 Elevated, elevation liver function test R79.89 ICD-10-CM Diagnosis Code R79.89

What is the ICD 10 code for signs and symptoms?

948 Signs and symptoms without mcc. Diagnosis Index entries containing back-references to R74.8: ICD-10-CM Diagnosis Code R74.9 ICD-10-CM Diagnosis Code R79.89 ICD-10-CM Codes Adjacent To R74.8 Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

What is ICD-10 code D66?

ICD-10 code D66 for Hereditary factor VIII deficiency is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .

How do you code an elevated INR?

Raised INR can be coded with the ICD-10 code R79. 8 Other specified abnormal findings of blood chemistry.

What is the ICD-10 for hemophilia?

D68. 311 - Acquired hemophilia | ICD-10-CM.

What is the ICD-10 code for subtherapeutic INR?

'Subtherapeutic INR levels' means that the patient is underwarfarinised, therefore as per ACS 0303 the correct code to assign is D68. 8 Other specified coagulation defects.

What is diagnosis code Z51 81?

ICD-10 code Z51. 81 for Encounter for therapeutic drug level monitoring is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .

What is the difference between G0250 and 93793?

G0250 and 93793 are similar but with a key difference: The difference is where the lab test was done. Use of code G0250 is not more than once a week, and is only used for home testing of INR. 93793 is used for review and management of a new test done at home, in the office or in the lab.

What causes elevated factor VIII levels?

Factor VIII levels can be elevated in a number of clinical conditions including carcinoma, leukemia, liver disease, renal disease, hemolytic anemia, diabetes mellitus, deep vein thrombosis, and myocardial infarction.

What is the ICD 10 code for classical hemophilia?

D68. 311 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D68. 311 became effective on October 1, 2021.

What is Haemophilia B?

Hemophilia B is a hereditary bleeding disorder caused by a lack of blood clotting factor IX. Without enough factor IX, the blood cannot clot properly to control bleeding.

What is a subtherapeutic INR?

1. Less than adequately treated. 2. Taking a drug with a blood level below a desired treatment range. Patients using warfarin for atrial fibrillation, for example, have subtherapeutic anticoagulation when their international normalized ratio (INR) is below 2.0.

What does it mean to have a high INR?

An international normalized ratio (INR) is a blood test that indicates how well the blood is able to clot. People who take warfarin (Coumadin) need to monitor this level to make sure it doesn't go too high or too low. If the INR is too high, you are at increased risk of bleeding.

What happens if your INR is high?

The higher your PT or INR, the longer your blood takes to clot. An elevated PT or INR means your blood is taking longer to clot than your healthcare provider believes is healthy for you. When your PT or INR is too high, you have an increased risk of bleeding.

How is factor VIII activity determined?

Factor VIII activity is determined utilizing an aPTT-based one-stage clotting time assay . Factor VIII-depleted plasma is used as the substrate and the clotting time with the patient plasma is compared to the clotting time of normal pooled plasma.

Where is factor VIII produced?

Factor VIII is a large glycoprotein cofactor (320 kilodaltons) that is produced mainly in hepatocytes, but also to some extent by liver macrophages, megakaryocytes, and endothelial cells. 6,10 Factor VIII circulates in the plasma bound to von Willebrand factor (vWF) at a concentration of approximately 0.1 mg/mL. 10 The plasma half-life of factor VIII is short at about 8 to 10 hours. 10 Factor VIII deficiency should be suspected when a patient with excessive bleeding has a normal protime (PT) and an extended activated partial thromboplastin time (aPTT).

Can lupus cause low factor VIII?

A lupus anticoagulant may cause factor VIII activity to appear spuriously low and a chromogenic factor VIII activity is recommended in this circumstance.

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D68.59:

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code (s). The following references for the code D68.59 are found in the index:

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Convert D68.59 to ICD-9 Code

The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D68.59 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.

Information for Patients

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code R76.8:

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code (s). The following references for the code R76.8 are found in the index:

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Convert R76.8 to ICD-9 Code

The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code R76.8 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.

What is factor VIII?

High levels of factor VIII are a risk factor for thrombosis, with a greater impact on venous than on arterial thrombosis. This risk is dose dependent for venous thrombosis, and factor VIII levels ≥150 IU/dL account for 16% of all venous thrombotic events, whereas factor VIII levels>123 IU/dL explain 4% of all arterial events. High factor VIII levels may increase the risk of venous thrombosis via enhanced thrombin formation and/or through the induction of acquired APC resistance. The relationship between factor VIII and arterial thrombosis may be based on the combination of increased thrombin formation and increased platelet adhesion/aggregation, induced by vWF, at sites of arterial wall damage.

What is the role of factor VIII in venous thrombotic risk?

After its activation by thrombin, factor VIIIa dissociates from vWF to form a complex with factor IXa, which will result in marked acceleration of the activation of factor X. 115 Activated factor X then converts prothrombin into thrombin, which in turn converts soluble fibrinogen into insoluble fibrin. It is possible that high factor VIII levels just increase the rate of thrombin and fibrin formation (in plasma, there is a large molar excess of factor IX over factor VIII).

Does factor VIII increase with age?

336364 Factor VIII levels increase with age, with an average rise of 5 to 6 IU/dL per decade. 4663 Oral contraceptives seem to have no effect on factor VIII levels. 6365

Does factor VIII protect against ischemic heart disease?

In 1989, a study by Rosendaal et al 82 reported that low factor VIII levels protect against ischemic heart disease. Mortality due to ischemic heart disease is much lower in patients with hemophilia A than in the general male population, 8283 which may suggest that factor VIII is involved in the pathogenesis of arterial thrombosis. Also vWF, the main determinant of the factor VIII level in plasma, may play a role in the pathogenesis of atherothrombosis. Autopsy findings from patients with severe von Willebrand disease have shown extensive atherosclerosis but no occlusive arterial thrombi, 8485 which suggests that even very low vWF levels may not fully protect against the development of atherosclerotic lesions. Similarly, dogs with severe von Willebrand disease and undetectable vWF levels did not develop acute occlusive thrombi in atherosclerotic arteries, 86 suggesting that vWF supports the progression of microthrombi into occlusive thrombosis.