Homocysteine. Homocysteine is an amino acid. Vitamins B12, B6 and folate break down homocysteine to create other chemicals your body needs. High homocysteine levels may mean you have a vitamin deficiency. Without treatment, elevated homocysteine increases your risks for dementia, heart disease and stroke. Appointments & Access.
Some common conditions associated with high homocysteine are:
Homocysteine is an amino acid produced when proteins are broken down. A high homocysteine level, also called hyperhomocysteinemia, can contribute to arterial damage and blood clots in your blood vessels. High homocysteine levels usually indicate a deficiency in vitamin B-12 or folate.
Serum homocysteine levels will not be covered other than for suspected B12/folate deficiency, or for risk stratification for the conditions noted in the ICD-10 Codes that Support Medical Necessity section of this Billing and Coding: Homocysteine Level, Serum A56675 article.
If your results show high homocysteine levels, it may mean: You are not getting enough vitamin B12, B6, or folic acid in your diet. You are at a higher risk of heart disease. Homocystinuria. If high levels of homocysteine are found, more testing will be needed to rule out or confirm a diagnosis.
Definition of homocysteine : an amino acid C4H9NO2S that is produced in animal metabolism by the demethylation of methionine and that appears to be associated with an increased risk of cardiovascular disease when occurring at high levels in the blood.
Homocysteine is an intermediary amino acid formed by the conversion of methionine to cysteine (figure 1). Homocystinuria is a rare autosomal recessive disorder characterized by severe elevations in plasma and urine homocysteine concentrations.
Most people who have a high homocysteine level don't get enough folate (also called folic acid), vitamin B6, or vitamin B12 in their diet. Replacing these vitamins often helps return the homocysteine level to normal. Other possible causes of a high homocysteine level include: Low levels of thyroid hormone.
A homocysteine test is a blood test. It measures the amount of homocysteine, an amino acid in the body. The test is often used to diagnose vitamin B6, B9 or B12 deficiency. People with elevated homocysteine may have a higher risk for cardiovascular disease.
In this page you can discover 14 synonyms, antonyms, idiomatic expressions, and related words for homocysteine, like: cholesterol, triglyceride, ldl cholesterol, fibrinogen, atherogenic, , folate, crp, cortisol, haemoglobin and HDL-C.
Serum homocysteine and methylmalonic acid (MMA) levels are helpful confirmatory tests for cobalamin and folate deficiencies. Both are increased in cobalamine deficiency. Homocysteine but not MMA is increased in folate deficiency.
Although combined folic acid and B-vitamin therapy substantially reduces homocysteine levels, results from randomized placebo-controlled clinical trials testing the effect of vitamin therapy on outcome in these diseases are mixed, but have generally fallen short of expectations.
Tests that can detect elevated levels of homocysteine, methionine, or homocysteine in the plasma or urine may be used to help confirm a diagnosis of homocystinuria. Usually individuals will undergo genetic testing looking for changes in both copies of the CBS gene to confirm their diagnosis.
CPT codes, descriptions and other data only are copyright 2021 American Medical Association. All Rights Reserved. Applicable FARS/HHSARS apply.
Title XVIII of the Social Security Act §1833 (e) prohibits Medicare payment for any claim which lacks the necessary information to process the claim.
The information in this article contains billing, coding or other guidelines that complement the Local Coverage Determination (LCD) for Homocysteine Level, Serum L34419.
The correct use of an ICD-10 code listed below does not assure coverage of a service. The service must be reasonable and necessary in the specific case and must meet the criteria specified in the Homocysteine Level, Serum L34419 LCD.
Contractors may specify Bill Types to help providers identify those Bill Types typically used to report this service. Absence of a Bill Type does not guarantee that the article does not apply to that Bill Type.
Contractors may specify Revenue Codes to help providers identify those Revenue Codes typically used to report this service. In most instances Revenue Codes are purely advisory. Unless specified in the article, services reported under other Revenue Codes are equally subject to this coverage determination.
CPT codes, descriptions and other data only are copyright 2021 American Medical Association. All Rights Reserved. Applicable FARS/HHSARS apply.
Documentation Requirements Documentation supporting medical necessity should be legible, maintained in the patient's medical record, and must be made available to the A/B MAC upon request. The patient's medical record must contain documentation that fully supports the medical necessity for services included within this Local Coverage Determination (LCD) (see Coverage Indications, Limitations and/or Medical Necessity ).