Heterozygous means that the 2 copies of a gene are different. In your case, one of your Factor V gene codes is for normal clotting Factor V and the other Factor V gene code is for Factor V Leiden. There is more risk of a blood clot if both gene codes are for Factor V Leiden (ie in the homozygous state).
Z83. 2 - Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism | ICD-10-CM.
ICD-10 code D68. 52 for Prothrombin gene mutation is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .
D68. 2 - Hereditary deficiency of other clotting factors. ICD-10-CM.
This testing is considered investigational and is NOT a Medicare benefit.
ICD-10 Code for Family history of carrier of genetic disease- Z84. 81- Codify by AAPC. Factors influencing health status and contact with health services. Persons with potential health hazards related to family and personal history and certain conditions influencing health status.
If you get the mutation from one of your parents, you are heterozygous (you have only one abnormal copy of the Factor II gene, but the gene from your other parent is normal). In heterozygous carriers of this mutation, the risk of developing a deep vein thrombosis or pulmonary embolism is about two to three in 1,000.
Factor II Mutation (Prothrombin Gene Mutation G20210A) (DNA Analysis)Test IDLAB5668CPT Codes81240Group/Individual TestIndividual (Can also be ordered as a Factor II/Factor V Mutation Panel-Lab12500)LaboratoryMolecular Genetics LaboratoryTube Station308 more rows•Apr 8, 2022
Prothrombin is a protein in the blood that is required for the blood to clot. It is also called factor II. Blood clots are composed of a combination of blood platelets and a meshwork of the blood clotting protein fibrin.
Factor VII, also called proconvertin, is one such clotting factor produced by the liver. It requires vitamin K for its production. Along with other clotting factors and blood cells, it promotes blood clotting at the site of an injury. It forms normal blood clots and closes the wound to prevent blood loss.
Factor V(5) Leiden is the most common genetic condition that can lead to blood clots. Almost all people with factor V Leiden have one affected gene and one normal gene.
The factor VII assay is a blood test to measure the activity of factor VII. This is one of the proteins in the body that helps the blood clot.
Factor v leiden mutation (r506q) is the most common cause of apc resistance. An abnormality that refers to mutation of factor v leiden, which is a variant of human factor v. It results in thrombophilia, deep vein thrombosis, and a slightly increased risk of miscarriage.
Group 1CodeDescription81241F5 (COAGULATION FACTOR V) (EG, HEREDITARY HYPERCOAGULABILITY) GENE ANALYSIS, LEIDEN VARIANT81291MTHFR (5,10-METHYLENETETRAHYDROFOLATE REDUCTASE) (EG, HEREDITARY HYPERCOAGULABILITY) GENE ANALYSIS, COMMON VARIANTS (EG, 677T, 1298C)1 more row
Thrombophilia is a blood disorder that makes the blood in your veins and arteries more likely to clot. This is also known as a "hypercoagulable" condition because your blood coagulates or clots more easily. Thrombophilia can be an inherited (genetic) or acquired tendency to form blood clots both in arteries and veins.
Factor V (factor 5) is one of several special proteins in your blood that help it clot. They're called clotting factors. Once the bleeding stops, other proteins tell your clotting factors to break up the clot, and it goes away. Factor V Leiden makes it harder for your clots to break up.