R65.21 | Severe sepsis with shock |
---|---|
N39.0 | UTI, site not specified |
R30.0 | Dysuria |
R50.81 | Fever presenting with conditions classified elsewhere |
N17.9 | Acute kidney failure, unspecified |
Bacterial vaginosis (BV), also known as vaginal bacteriosis or Gardnerella vaginitis, is a disease of the vagina caused by excessive growth of bacteria. Common symptoms include increased vaginal discharge that often smells like fish. The discharge is usually white or gray in color. Burning with urination may occur. Itching is uncommon.
The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code B96. Click on any term below to browse the alphabetical index.
Arthritis of left shoulder caused by bacteria; Bacterial arthritis of bilateral shoulders; Bacterial arthritis of left shoulder. ICD-10-CM Diagnosis Code M00.812. Arthritis due to other bacteria, left shoulder.
Arthritis of right elbow caused by bacteria; Bacterial arthritis of bilateral elbows; Bacterial arthritis of right elbow. ICD-10-CM Diagnosis Code M00.821. Arthritis due to other bacteria, right elbow.
Trichomonas can also be detected by by DNA probes amplified by polymerase chain reaction. Sample is treated with enzymes that amplify specific regions of trichomonas vaginalis' DNA.
Vaginitis (infection of the vagina) is the most common gynecologic condition encountered by physicians in the office. Patients with vaginitis almost always present with a chief complaint of abnormal vaginal discharge. The most common causes of vaginitis are trichomoniasis ( Trichomonas vaginalis infection ), vaginal candidiasis ( Candida vaginalis ), and bacterial vaginosis (BV).
DNA probes have been developed to directly detect the presence of candida, trichomonas and Gardnerella, thus providing a more objective diagnosis. Since Gardnerella is a normal part of the vaginal flora, the DNA probe test is designed to be relatively insensitive, detecting only pathogenic levels of Gardnerella.
Trichomonas can also be detected by by DNA probes amplified by polymerase chain reaction. Sample is treated with enzymes that amplify specific regions of trichomonas vaginalis' DNA. After amplification, the number of DNA fragments are quantified.
Hong and colleagues (2016) stated that next-generation se quencing (NGS) can detect many more microorganisms of a microbiome than traditional methods. These researchers analyzed the vaginal microbiomes of Korean women by using NGS that included bacteria and other microorganisms. The NGS results were compared with the results of other assays, and NGS was evaluated for its feasibility for predicting vaginitis. A total of 89 vaginal swab specimens were collected. Microscopic examinations of Gram staining and microbiological cultures were conducted on 67 specimens; NGS was performed with GS junior system on all of the vaginal specimens for the 16S rRNA, internal transcribed spacer (ITS), and Tvk genes to detect bacteria, fungi, and Trichomonas vaginalis. In addition, DNA probe assays of the Candida spp., Gardnerella vaginalis, and Trichomonas vaginalis were performed. Various predictors of diversity that were obtained from the NGS data were analyzed to predict vaginitis; ITS sequences were obtained in most of the specimens (56.2 %). The compositions of the intermediate and vaginitis Nugent score groups were similar to each other, but differed from the composition of the normal score group. The fraction of the Lactobacillus spp. showed the highest area under the curve value (0.8559) in ROC curve analysis. The NGS and DNA probe assay results showed good agreement (range of 86.2 to 89.7 %). The authors concluded that fungi as well as bacteria should be considered for the investigation of vaginal microbiome. The intermediate and vaginitis Nugent score groups were indistinguishable in NGS. They stated that NGS is a promising diagnostic tool of the vaginal microbiome and vaginitis, although some problems need to be resolved.
Schwebke and colleagues (2018) determined the characteristics of an investigational test (BD MAX vaginal panel, a molecular test for vaginitis), compared to reference, for detection of bacterial vaginosis, Candida spp., and Trichomonas vaginalis. Vaginal specimens from a cross-sectional study were obtained from 1,740 women (greater than or equal to 18 years old), with vaginitis symptoms, during routine clinic visits (across 10 sites in the United States). Specimens were analyzed using a commercial PCR/fluorogenic probe-based investigational test that detects bacterial vaginosis, candida spp., and trichomonas vaginalis. Clinician diagnosis and in-clinic testing (Amsel's test, potassium hydroxide preparation, and wet mount) were also employed to detect the 3 vaginitis causes. All testing methods were compared to the respective reference methods (Nugent Gram stain for bacterial vaginosis, detection of the candida gene its2, and trichomonas vaginalis culture). The investigational test, clinician diagnosis, and in-clinic testing were compared to reference methods for bacterial vaginosis, candida spp., and trichomonas vaginalis. The investigational test resulted in significantly higher sensitivity and negative predictive value than clinician diagnosis or in-clinic testing. In addition, the investigational test showed a statistically higher overall percent agreement with each of the 3 reference methods than did clinician diagnosis or in-clinic testing. The investigational test showed significantly higher sensitivity for detecting vaginitis, involving more than one cause, than did clinician diagnosis. Taken together, these results suggested that a molecular investigational test can facilitate accurate detection of vaginitis. The authors concluded that findings from the current study supported the potential utility of the investigational test in the differential diagnosis of vaginitis. While some laboratory tests take 2 to 7 days to provide results, the investigational test results were generally available within 24 hours. Moreover, they stated that although future work is needed to establish the cost/benefit ratio regarding the application of this investigational test in a practical setting, its high sensitivity, specificity, and accuracy (across a large spectrum of disease prevalence) should impart benefits and decrease the chance of needless treatment of patients that are negative for the disease. This may prove especially important with cases of vaginitis that involve multiple causes, where the sensitivity of clinician diagnosis may be limited.
Bacterial vaginosis (BV), also known as vaginal bacteriosis or Gardnerella vaginitis, is a disease of the vagina caused by excessive growth of bacteria. Common symptoms include increased vaginal discharge that often smells like fish. The discharge is usually white or gray in color. Burning with urination may occur. Itching is uncommon.
DRG Group #867-869 - Other infectious and parasitic diseases diagnoses with MCC.
This is the official exact match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that in all cases where the ICD9 code 041.82 was previously used, B96.6 is the appropriate modern ICD10 code.