icd 10 code for hemoglobin h disease

How many codes in ICD 10?

Hb-SS disease with (painful) crisis NOS. Hb-SS disease with vasoocclusive pain NOS. ICD-10-CM Diagnosis Code D56.4 [convert to ICD-9-CM] Hereditary persistence of fetal hemoglobin [HPFH] Hereditary persistence of fetal hemoglobin thalassemia; Thalassemia, persistence of fetal hemoglobin. ICD-10-CM Diagnosis Code D56.4.

What does ICD - 10 stand for?

 · D58.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D58.2 became effective on October 1, 2021. This is the American ICD-10-CM version of D58.2 - other international versions of ICD-10 D58.2 may differ. Applicable To Abnormal hemoglobin NOS

What is the ICD 10 diagnosis code for?

ICD-10-CM Diagnosis Code D56.4. Hereditary persistence of fetal hemoglobin [HPFH] 2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code. H Constant Spring D56.0. ICD-10-CM Diagnosis Code D56.0. Alpha thalassemia. 2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code. Applicable To. Alpha thalassemia major.

What are ICD 10 codes?

There are 8 terms under the parent term 'Hemoglobin Disease' in the ICD-10-CM Alphabetical Index. Hemoglobin Disease - see also condition abnormal (disease) - see Disease, hemoglobin AS genotype D57.3 Constant Spring D58.2 E-beta thalassemia D56.5 fetal, hereditary persistence (HPFH) D56.4 H Constant Spring D56.0 low NOS D64.9 S (Hb S) , heterozygous D57.3

What is the meaning of hemoglobin H disease?

Hemoglobin H disease (HbH) is a form of alpha thalassemia in which moderately severe anemia develops due to reduced formation of alpha globin chains. In this condition, as in the other forms of thalassemia, there is an imbalance of globin chains needed to form hemoglobin.

Is hemoglobin H disease thalassemia?

An intermediate form of alpha-thalassemia characterized by increased hemolysis and mild to severe anemia with marked microcytosis and hypochromia. Hemoglobin H disease (HbH) disease belongs to the group of nontransfusion-dependent thalassemia.

What causes hemoglobin H disease?

Hemoglobin H disease, or α-thalassemia intermedia, occurs as a result of deletion mutations of three of four α-globin genes, causing a deficiency of the α-globin chains of hemoglobin and an excess production of β-globin chains.

What is the ICD-10 code for thalassemia trait?

ICD-10 code D56. 3 for Thalassemia minor is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .

What is Hemoglobin H inclusion?

Hemoglobin H, consisting of beta chain tetramers, is an unstable hemoglobin which forms precipitates just below the red blood cell membrane. This precipitated hemoglobin inclusion can be observed when red blood cells are stained with Brilliant Cresyl Blue (BCB). Hemoglobin H bodies are seen as faint blue inclusions.

What are the 4 types of thalassemia?

Alpha thalassemia occurs when some or all of the 4 genes that make hemoglobin (the alpha-globin genes) are missing or damaged....There are 4 types of alpha thalassemia:Alpha thalassemia silent carrier. ... Alpha thalassemia carrier. ... Hemoglobin H disease. ... Alpha thalassemia major.

What is the difference between sickle cell anemia and thalassemia?

Thalassemia is a quantitative problem of too few globins synthesized, whereas sickle-cell anemia (a hemoglobinopathy) is a qualitative problem of synthesis of an incorrectly functioning globin. Thalassemias usually result in underproduction of normal globin proteins, often through mutations in regulatory genes.

What is the difference between thalassemia and anemia?

Anemia is a condition in which your body doesn't have enough normal, healthy red blood cells. Thalassemia is inherited, meaning that at least one of your parents must be a carrier of the disorder. It's caused by either a genetic mutation or a deletion of certain key gene fragments.

What is the difference between alpha thalassemia and beta thalassemia?

When thalassemia is called “alpha” or “beta,” this refers to the part of hemoglobin that isn't being made. If either the alpha or beta part is not made, there aren't enough building blocks to make normal amounts of hemoglobin. Low alpha is called alpha thalassemia. Low beta is called beta thalassemia.

What's beta thalassemia?

What is beta thalassemia? Thalassemia (thal-uh-SEE-mee-uh) is a blood disorder that is inherited. This means it is passed down from one or both parents through their genes. When you have thalassemia, your body makes less hemoglobin than normal. Hemoglobin is an iron-rich protein in red blood cells.

What is thalassemia major and minor?

Beta-thalassemia One mutated gene, you'll have mild signs and symptoms. This condition is called thalassemia minor or beta-thalassemia. Two mutated genes, your signs and symptoms will be moderate to severe. This condition is called thalassemia major, or Cooley anemia.

What is alpha thalassemia trait?

Alpha thalassemia (thal uh SEE mee uh) trait is a condition that affects the amount of hemo- globin in the red blood cells. • Adult hemoglobin (hemoglobin A) is made of alpha and beta globins. • Normally, people have 4 genes for alpha globin with 2 genes on each chromosome (αα/αα).

What genotype represents Hb H disease?

Genotypes of Hb H disease They include initiation codon mutation (ATG>ACG), Hb Sallanches (codon 104 TGC>TAC or Cys→Tyr), or polyadenylation signal mutation (AATAAA>AATAAG). 25,29,34-37 Even in this small subset of patients, their phenotypes can vary from relatively mild to very severe, requiring regular transfusions.

What type of anemia is beta thalassemia?

Beta thalassemia is classified into two types depending on the severity of symptoms: thalassemia major (also known as Cooley's anemia) and thalassemia intermedia. Of the two types, thalassemia major is more severe. The signs and symptoms of thalassemia major appear within the first 2 years of life.

How do you treat hemoglobin H?

Treating Hemoglobin H Disease In particular, these include hemolytic and aplastic anemic episodes. Folic acid supplements and avoidance of oxidative compounds and medications are recommended. In mild cases, biannual visits are adequate. In more severe cases, more frequent visits are indicated.

Is alpha thalassemia common?

Alpha thalassemia is a fairly common blood disorder worldwide. Thousands of infants with Hb Bart syndrome and HbH disease are born each year, particularly in Southeast Asia. Alpha thalassemia also occurs frequently in people from Mediterranean countries, Africa, the Middle East, India, and Central Asia.

What is the structural change of a hemoglobin?

Hemoglobins characterized by structural alterations within the molecule. The alteration can be either absence, addition or substitution of one or more amino acids in the globin part of the molecule at selected positions in the polypeptide chains.

What is a hemolytic disorder?

A disease characterized by compensated hemolysis with a normal hemoglobin level or a mild to moderate anemia. There may be intermittent abdominal discomfort, splenomegaly, and slight jaundice. A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.

When will the ICd 10 D58.2 be released?

The 2022 edition of ICD-10-CM D58.2 became effective on October 1, 2021.

What is a heme disorder?

A genetic hematologic disorder characterized by partial or complete absence of the alpha globin chains of the heme molecule.

When will the ICd 10 D56.0 be released?

The 2022 edition of ICD-10-CM D56.0 became effective on October 1, 2021.

When will the ICd 10 D56.8 be released?

The 2022 edition of ICD-10-CM D56.8 became effective on October 1, 2021.

What is D50-D89?

D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

What is the ICd10 code for hemoglobinopathies?

The ICD10 code for the diagnosis "Other hemoglobinopathies" is "D58.2". D58.2 is a VALID/BILLABLE ICD10 code, i.e it is valid for submission for HIPAA-covered transactions.

When did ICD-10 D58.2 become effective?

The 2019 edition of ICD-10-CM D58.2 became effective on October 1, 2018.