These tests are used to decide how much medicine you need.
Thrombocytopenia, unspecified D69. 6 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
What increases my risk for HIT?
UW Medicine Standard Protocols – Initiation Dosing
ICD-10 | Heparin induced thrombocytopenia (HIT) (D75. 82)
82.
Heparin‐induced thrombocytopenia (HIT) is a potentially devastating immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin.
What Is Heparin-Induced Thrombocytopenia? Ordinarily, heparin prevents clotting and does not affect the platelets, components of the blood that help form blood clots. Triggered by the immune system in response to heparin, HIT causes a low platelet count (thrombocytopenia).
ICD-10 code D69. 6 for Thrombocytopenia, unspecified is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .
Diagnosis of HIT is based on clinical assessment and laboratory results. Primary laboratory tests for HIT include immunologic assays, such as an enzyme-linked immunosorbent assay (ELISA), and functional, platelet-activation assays, such as the serotonin release assay (SRA).
Type 1 HIT is a nonimmune disorder that results from the direct effect of heparin on platelet activation. Type 2 HIT is an immune-mediated disorder that typically occurs 4-10 days after exposure to heparin and has life- and limb-threatening thrombotic complications.
Heparin-induced thrombocytopenia (HIT) occurs when a patient receives heparin, a blood-thinning medication, and subsequently forms antibodies against heparin and the platelet factor-4 (PF4) complex.
Treatment of HIT entails immediate withdrawal of all heparin, including heparin-containing flushes and catheters. Heparin cessation alone, however, is often insufficient to prevent thrombosis.
Although antithrombotic therapy with LMWH is known to be safer than therapy with UFH, enoxaparin-induced thrombocytopaenia can occur. Even though enoxaparin-induced thrombocytopaenia occurred less often than HITS in one study, the clinical manifestations of both were similar.
If thrombocytopenia develops within the first 24 hours of heparin exposure, HIT is considered in patients who have had recent (100 days or less) heparin exposure, because they may have preformed heparin-PF4 antibodies.
In 2021 a condition resembling HIT but without heparin exposure was described to explain unusual post-vaccination embolic and thrombotic events after the Oxford–AstraZeneca COVID-19 vaccine. It is a rare adverse event (1:1 million to 1:100,000) resulting from COVID-19 vaccines (particularly adenoviral vector vaccines).
Macrocytosis is the enlargement of red blood cells with near-constant hemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories). The enlarged erythrocytes are called macrocytes or megalocytes (both words have roots meaning "big cell").
The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code D75.82. Click on any term below to browse the alphabetical index.
This is the official exact match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that in all cases where the ICD9 code 289.84 was previously used, D75.82 is the appropriate modern ICD10 code.