Hypoxic brain damage, also called hypoxic–ischemic encephalopathy, is a severe consequence of global cerebral ischemia due to cardiac arrest [1] or other causes (e.g. hanging, strangulation, poisoning with carbon monoxide or near-drowning).
Hypoxic-ischemic cerebral injury occurs at any age, although the etiology is significantly different: older children: drowning and asphyxiation remain common causes. adults: more often a result of cardiac arrest or cerebrovascular disease, with secondary hypoxemia/hypoperfusion.
Hypoxic-Ischemic Encephalopathy (or HIE) is a non-specific term for brain dysfunction caused by a lack of blood flow and oxygen to the brain. Sometimes, HIE is also referred to as birth asphyxia, but this term only pertains to a very strict criteria of infants with brain injury.
Abstract: Hypoxic-ischemic encephalopathy (HIE), is one of the most frequent and dramatic urgency found in neurological brain diseases of adults. This is a neuro-vascular and neuro-metabolic syndrome, caused by a shortage of supply of oxygen and glucose or their metabolism in the brain.
The pathogenesis of the brain damage remains unclear. We hypothesize that brain damage in AHT is due to hypoxic-ischemic injury with hypoxic-ischemic encephalopathy (HIE) rather than primary traumatic brain injury (TBI) with traumatic diffuse axonal injury (tDAI).
To confirm a diagnosis of HIE, a neurologist will examine your baby, who will be monitored by an electroencephalogram for seizures and signs of brain dysfunction and undergo neuroimaging tests, such as magnetic resonance imaging (MRI), to check for signs of brain injury.
Similarly, hypoxic-ischemic encephalopathy (HIE) is, at its core, an injury caused by a lack of oxygenated blood flow to the brain. Sometimes babies that are diagnosed with HIE will also suffer a perinatal stroke as a result of the HIE; it is very common for them to co-occur.
Hypoxic ischemic encephalopathy (HIE) is one of the most serious birth complications affecting full term infants. It occurs in 1.5 to 2.5 per 1000 live births in developed countries.
0:011:07Hypoxic-ischemic encephalopathy - Medical Meaning and PronunciationYouTubeStart of suggested clipEnd of suggested clipMay cause death in the newborn.MoreMay cause death in the newborn.
High-Risk Pregnancy and HIE Conditions that make a pregnancy high-risk include (but are certainly not limited to) the following: Obesity. Diabetes or gestational diabetes (when a woman develops diabetes during pregnancy) High blood pressure or preeclampsia (when a woman develops high blood pressure during pregnancy)
Definition. Cerebral hypoxia refers to a condition in which there is a decrease of oxygen supply to the brain even though there is adequate blood flow.
At present, there is no true cure for hypoxic-ischemic encephalopathy (HIE). However there is one treatment, called therapeutic hypothermia, that can reduce the extent of permanent brain damage if given very shortly after birth or the oxygen-depriving incident.
HIE is, unfortunately, not curable. It can also have varying levels of severity, so treatment options may significantly vary. Fortunately, there are many treatments and therapies that can improve function for children with HIE, as well as ways to manage the condition in the long term.
Global ischemia is worse than hypoxia, hypoglycemia, and seizures because, in addition to causing energy failure, it results in accumulation of lactic acid and other toxic metabolites that are normally removed by the circulation.
Neonates with hypoxic–ischemic encephalopathy typically present shortly after delivery with abnormalities in tone, posturing, and seizures. It can be difficult to differentiate stroke from hypoxic–ischemic encephalopathy in the neonate given overlapping presentations.
A full recovery from severe anoxic or hypoxic brain injury is rare, but many patients with mild anoxic or hypoxic brain injuries are capable of making a full or partial recovery. Furthermore, symptoms and effects of the injury are dependent on the area(s) of the brain that was affected by the lack of oxygen.