icd 10 code for inborn errors of metabolism

ICD-10-CM Alphabetical Index References for 'E88.9 - Metabolic disorder, unspecified'

The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code E88.9. Click on any term below to browse the alphabetical index.

Equivalent ICD-9 Code GENERAL EQUIVALENCE MAPPINGS (GEM)

This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code E88.9 and a single ICD9 code, 277.9 is an approximate match for comparison and conversion purposes.

What is the approximate match between ICd9 and ICd10?

This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code Z13.228 and a single ICD9 code, V77.99 is an approximate match for comparison and conversion purposes.

What is billable code?

Billable codes are sufficient justification for admission to an acute care hospital when used a principal diagnosis. The Center for Medicare & Medicaid Services (CMS) requires medical coders to indicate whether or not a condition was present at the time of admission, in order to properly assign MS-DRG codes.

What are inborn errors of metabolism?

Inborn errors of metabolism. Inborn errors of metabolism form a large class of genetic diseases involving congenital disorders of enzyme activities. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances ( substrates )) into others ( products ). In most of the disorders, problems arise ...

Who first studied inborn errors of metabolism?

Finally, inborn errors of metabolism was studied, for the first time, by a British physician, Archibald Garrod (1857–1936), in 1908.

What is the term for inherited metabolic disorders?

In most of the disorders, problems arise due to accumulation of substances which are toxic or interfere with normal function, or to the effects of reduced ability to synthesize essential compounds. Inborn errors of metabolism are now often referred to as congenital metabolic diseases or inherited metabolic disorders.

What are metabolic diseases?

Traditionally the inherited metabolic diseases were classified as disorders of carbohydrate metabolism, amino acid metabolism, organic acid metabolism, organic acid metabolism, or lysosomal storage diseases. In recent decades, hundreds of new inherited disorders of metabolism have been discovered and the categories have proliferated. Following are some of the major classes of congenital metabolic diseases, with prominent examples of each class.

What are inborn errors of metabolism?

Inborn errors of metabolism comprise a large class of genetic diseases involving disorders of metabolism. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances ( substrates) into others ( products ). In most of the disorders, problems arise due to accumulation of substances which are toxic or interfere with normal function, or to the effects of reduced ability to synthesize essential compounds. Inborn errors of metabolism are now often referred to as congenital metabolic diseases or inherited metabolic diseases, and these terms are considered synonymous.

Who coined the term "inborn error of metabolism"?

The term inborn error of metabolism was coined by a British physician, Archibald Garrod (1857-1936), in the early 20th century (1908). He is known for the "one gene, one enzyme" hypothesis, which arose from his studies on the nature and inheritance of alkaptonuria. His seminal text, Inborn Errors of Metabolism was published in 1923.

What are the best resources for inborn errors of metabolism?

For clinicians and scientists in the field of inborn errors of metabolism, good resources include books by Scriver . Fernandes , Clarke , Blau (diagnosis) , Blau (treatment) , Lyon , Nyhan , Hoffmann and Zschocke . Other ressources include genetests, orphanet, OMIM, Metab-L ,societies such as the SSIEM, the SIMD and links therein. For medical students and clinicians looking for overviews of the field, such reviews can be found on pubmed and in good pediatric textbooks (e.g. articles by Saudubray, Ellaway, Raghuveer or Burton and textbooks by Hay or Behrman ).

Can you detect metabolic diseases in newborns?

Dozens of congenital metabolic diseases are now detectable by newborn screening tests, especially the expanded testing using mass spectrometry. This is an increasingly common way for the diagnosis to be made and sometimes results in earlier treatment and a better outcome.