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ICD coding 1 ICD-O: 8825/1 - Inflammatory myofibroblastic tumor 2 ICD-10: D48.9 - Neoplasm of uncertain behavior, unspecified 3 ICD-11: 2B53.Y & XH66Z0 - Other specified fibroblastic or myofibroblastic tumor, primary site and myofibroblastic tumor, NOS
ICD-O: 8825/1 - Inflammatory myofibroblastic tumor ICD-10: D48.9 - Neoplasm of uncertain behavior, unspecified ICD-11: 2B53.Y & XH66Z0 - Other specified fibroblastic or myofibroblastic tumor, primary site and myofibroblastic tumor, NOS
How common is inflammatory myofibroblastic tumor? IMT is very rare and occurs in less than one in one million people. An estimated 150-200 people are diagnosed in the US annually. How is inflammatory myofibroblastic tumor diagnosed?
M72.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM M72.9 became effective on October 1, 2021. This is the American ICD-10-CM version of M72.9 - other international versions of ICD-10 M72.9 may differ. A condition in which multiple fibromas develop.
An Inflammatory myofibroblastic tumor (IMT) is an uncommon, usually benign (non-cancerous) tumor made up of cells called myofibroblastic spindle cells. It usually develops in children or young adults, but can affect people of any age.
Inflammatory myofibroblastic tumors usually occur in children and young adults. They are a type of soft tissue sarcoma.
Low-grade myofibroblastic sarcoma (LGMS) is a malignant lesion composed of myofibroblasts. It is an uncommon tumor of unknown etiology that mainly develops in the bone or soft tissue and is most often reported in the head and neck, particularly in the tongue and oral cavity.
Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a variant of myofibroblastic tumor with malignant characteristics; it mainly consists of round-to-epithelioid cells with positive nuclear membrane/perinuclear immunostaining for anaplastic lymphoma kinase (ALK) receptor tyrosine kinase.
Histopathologically, myofibroblastic sarcomas (MFS) are composed of slender spindle cells with variable nuclear pleomorphism and mitotic activity. The spindle cells are arranged in interlacing fascicles and have eosinophilic cytoplasm, which may be occasionally wavy.
Stage I soft tissue sarcomas are low-grade tumors of any size. Small (less than 5 cm or about 2 inches across) tumors of the arms or legs may be treated with surgery alone. The goal of surgery is to remove the tumor with some of the normal tissue around it.
Leiomyosarcoma, or LMS, is a type of rare cancer that grows in the smooth muscles. The smooth muscles are in the hollow organs of the body, including the intestines, stomach, bladder, and blood vessels. In females, there is also smooth muscle in the uterus.
Nodular fasciitis is a fast-growing lump in your soft tissue. It's not clear why you get it, but it's not cancerous. It's sometimes called pseudosarcomatous fasciitis, proliferative fasciitis, or infiltrative fasciitis. It's a noncancerous skin growth in your soft tissue.
Cite this page: Bennett J. Inflammatory myofibroblastic tumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/uterusinflammpseudo.html. Accessed February 23rd, 2022.
Cite this page: Bennett J. Inflammatory myofibroblastic tumor. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/uterusinflammpseudo.html. Accessed February 23rd, 2022.
Inflammatory myofibroblastic tumor is a rare neoplastic lesion of the submucosal stroma, which can develop in any organ, often occurring in the lung, mesentery, omentum and the retroperitoneal region. It is histologically heterogenous, composed of spindle-shaped cells, myofibroblasts and inflammatory cells.
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Inflammation of the fascia. There are three major types: 1, eosinophilic fasciitis, an inflammatory reaction with eosinophilia, producing hard thickened skin with an orange-peel configuration suggestive of scleroderma and considered by some a variant of scleroderma; 2, necrotizing fasciitis (fasciitis, necrotizing), a serious fulminating infection (usually by a beta hemolytic streptococcus) causing extensive necrosis of superficial fascia; 3, nodular/pseudosarcomatous /proliferative fasciitis, characterized by a rapid growth of fibroblasts with mononuclear inflammatory cells and proliferating capillaries in soft tissue, often the forearm; it is not malignant but is sometimes mistaken for fibrosarcoma.
A condition in which multiple fibromas develop. Fibromas are tumors (usually benign) that affect connective tissue. A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern.
The 2022 edition of ICD-10-CM M72.9 became effective on October 1, 2021.
PubMed is a searchable database of medical literature and lists journal articles that discuss Inflammatory myofibroblastic tumor. Click on the link to view a sample search on this topic.
Listen. An inflammatory myofibroblastic tumor (IMT) is an uncommon, usually benign (non-cancerous) tumor made up of cells called myofibroblastic spindle cells. It usually develops in children or young adults, but can affect people of any age. An IMT can occur in almost any part of the body but is most commonly found in the lung, orbit (eye socket), ...
A registry supports research by collecting of information about patients that share something in common, such as being diagnosed with Inflammatory myofibroblastic tumor. The type of data collected can vary from registry to registry and is based on the goals and purpose of that registry.
Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss Inflammatory myofibroblastic tumor. Click on the link to view a sample search on this topic.
One study found that a higher percentage of patients with localized disease were ALK-positive (about 60%) compared to those with multicentric (having 2 or more separate growths) IMTs (about 33%).
The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
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A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere.
The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes. Primary malignant neoplasms overlapping site boundaries.
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology] Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, ...
The 2022 edition of ICD-10-CM C49.9 became effective on October 1, 2021.
A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition. All neoplasms are classified in this chapter, whether they are functionally active or not.
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere.
Functional activity. All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology]
The 2022 edition of ICD-10-CM C49.0 became effective on October 1, 2021.
In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes. Primary malignant neoplasms overlapping site boundaries.
You can help speed up the development of new treatments by giving researchers the tools they need.
The estimate of how a disease will affect you long-term is called prognosis. Every person is different and prognosis will depend on many factors, such as:
IMT may also be called inflammatory fibrosarcoma or IMFT. IMT is named for two types of cells in the tumor. IMT forms from a type of cell called a myofibroblast. Myofibroblasts help keep the shape of organs and heal wounds. IMTs also contain a lot of immune cells, making the tumor look “inflamed” like an infection.
How is inflammatory myofibroblastic tumor diagnosed? Although IMT can cause specific symptoms, some people with IMT do not have any. IMT symptoms depend on where the tumor is and its size. Symptoms may include fever, night sweats, weight loss, generally not feeling well, and pain at the site of the tumor.
Given that there are so few IMT patients, these survival rates may not be very accurate. They also don’t consider newer treatments being developed. In general, those with IMT that is completely removed by surgery do very well and most people survive past 10 years.
Chemotherapy: If the IMT is faster growing or has returned after surgery, your doctor may use chemotherapy to treat it. Targeted Therapy: Some IMTs make proteins that can be targeted by new drugs. Depending on how well your IMT is removed by surgery, your doctor may try one of these targeted therapies.
Treatment of IMT depends on where the tumor is located, which proteins it makes, and whether it has spread to other parts of the body. Surgery: IMTs are hard to completely remove by surgery and often come back. It is important to follow up with your doctor to check if the tumor has returned.
A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as D48.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere.
Functional activity. All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology]
The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes. Primary malignant neoplasms overlapping site boundaries.
The 2022 edition of ICD-10-CM D48.1 became effective on October 1, 2021.