icd 10 code for jak2 mutation

What causes a Jak2 mutation?

Oct 01, 2021 · They all involve dysregulation of multipotent myeloid progenitor cells, most often caused by a mutation in the jak2 protein tyrosine kinase. ICD-10-CM D47.1 is grouped within Diagnostic Related Group (s) (MS-DRG v39.0): 820 Lymphoma and leukemia with major o.r. Procedures with mcc 821 Lymphoma and leukemia with major o.r. Procedures with cc

What does JAK 2 mutation mean?

Oct 28, 2017 · Jak2 mutation icd 10 code for hypothyroidism: Hypothyroidism D48 Neoplasm of uncertain behavior of other and unspecified sites. David Stewart Saturday, October 28, 2017 If the testing is negative, further testing to detect other JAK2 tyrosine kinase variants e. Similar to the CA antigen, CA is found in the blood of most breast cancer patients.

What is JAK 2 mutation test?

Apr 30, 2022 · jak2 (v617f) mutation, blood a.k.a. Essential Thrombocythemia, Idiopathic myelofibrosis, JAK2, Janus Kinase 2, Myeloproliferative Disorders, Polycythemia vera, Polycythemia vera., V617F Test information includes: LOINC codes diseases the test is often used to detect or monitor overview of the test utility - when/why/how the test is used

How rare is JAK 2 mutation?

Oct 01, 2021 · 2022 ICD-10-CM Diagnosis Code D68.52 Prothrombin gene mutation 2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code D68.52 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D68.52 became effective on October 1, 2021.

What is the JAK2 gene mutation?

What is the ICD 10 code for secondary thrombocytosis?

Is JAK2 a leukemia mutation?

What does JAK2 stand for?

Is thrombocytosis the same as thrombocythemia?

What is the ICD-10 diagnosis code for thrombocytosis?

How is JAK2 mutation acquired?

Is JAK2 curable?

Is JAK2 inherited?

What is a JAK2 mutation test?

What is JAK1 and JAK2?

How many JAK2 mutations are there?

What is blood typing?

Blood typing is a screening test to determine blood groups and Rh antigen for blood transfusion and pregnancy. The four blood groups A, B, O, and AB are determined by the presence of antigens A and B or their absence (O) on a patient's red blood cells.

Why is it important to have blood transfusions?

Transfusion of blood components of the correct blood type is necessary in order to prevent an adverse immunologic reaction. These reactions can range from very mild and sub-clinical to very severe or fatal, depending upon the components involved and condition of the recipient.

Special Instructions

Please provide indications for JAK2 testing and specimen type. Direct any questions regarding this test to customer service at 800-345-4363.

Expected Turnaround Time

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Collection

Submit at room temperature. Specimen should arrive at the testing laboratory within 48 hours of collection. Indicate the date and time of collection on the test request form.

Storage Instructions

Ship at room temperature. If specimen is to be stored prior to shipment, store at 2°C to 8°C.

Causes for Rejection

Specimen does not meet collection criteria; frozen whole blood, marrow, or cell pellet; leaking tube; clotted blood or marrow; grossly hemolyzed specimen or otherwise visibly degraded; contamination by another specimen; specimens containing suspicious foreign material.

Use

The quantitative real-time PCR assay detects V617F mutation (c.1849 G>T) observed in approximately 95% polycythemia vera (pv), 55% essential thrombocythemia (ET), and 55% primary myelofibrosis (PMF). It is also infrequently present (3% to 5%) in myelodysplastic syndrome, chronic myelomonocytic leukemia, and other atypical chronic myeloid disorders.

Limitations

This assay detects only the JAK2V617F point mutation. Other mutations that may occur in the JAK2 gene will not be detected. In vitro studies have indicated that this assay has an analytical sensitivity of 1%. This test was developed, and its performance characteristics determined, by LabCorp.

General Information

CPT codes, descriptions and other data only are copyright 2020 American Medical Association. All Rights Reserved. Applicable FARS/HHSARS apply.

Article Guidance

Article Text#N#Article Text#N#This article contains coding and other guidelines that complement the Local Coverage Determination (LCD) for Molecular Pathology Procedures.#N#Coding Information:#N#Coding guidance in this article is categorized into four, distinct CPT/HCPCS sections:#N#· CPT/HCPCS section-Group1- Tier 1 Covered Codes for which limited coverage may be provided for the genetic tests and for which specific ICD-10-CM diagnosis to CPT procedure groupings may be listed#N#· CPT/ HCPCS section-Group 2- Tier 1 Codes that require Individual Review for which coverage may be provided for the genetic tests submitted, if documentation supports medical necessity, and for which specific ICD-10-CM diagnosis to CPT procedure groupings may be listed.#N#· CPT/HCPCS section-Group 3- Tier 1 Non-covered Codes for which genetic testing is unlikely to impact therapeutic decision-making in the clinical management of the patient and will be denied automatically as not medically necessary.#N#· CPT/HCPCS section-Group 4- Tier 2/NOC Covered Code/Gene Combinations for which limited coverage may be provided for specific genes listed in the Group 4 paragraph; Tier 2/NOC Individual Review Code/Gene Combinations; Tier 2/NOC Non-covered Code/Gene Combinations.#N#Abstract:#N#According to The American Medical Association (AMA) Current Procedural Terminology (CPT) manual, molecular pathology procedures are medical laboratory procedures involving the analyses of nucleic acid to detect variants in genes that may be indicative of germline (e.g., constitutional disorders) or somatic (e.g., neoplasia) conditions, or to test for histocompatibility antigens (e.g., HLA).

ICD-10-CM Codes that Support Medical Necessity

CPT codes 81162-81167, 81212, 81215, 81216, 81217 are considered medically necessary for the following ICD-10-CM codes:

Bill Type Codes

Contractors may specify Bill Types to help providers identify those Bill Types typically used to report this service. Absence of a Bill Type does not guarantee that the article does not apply to that Bill Type.

Revenue Codes

Contractors may specify Revenue Codes to help providers identify those Revenue Codes typically used to report this service. In most instances Revenue Codes are purely advisory. Unless specified in the article, services reported under other Revenue Codes are equally subject to this coverage determination.