icd 10 code for long term use of prolia injection for osteoporosis

by Cassie Schroeder 6 min read

ICD-10-CM code Z90.721 or Z90.722 should be reported for women s/p oophorectomy. ICD-10-CM code Z79.51 or Z79.52 should be reported for an individual on glucocorticoid therapy. ICD-10-CM code Z79.83 should be reported for DXA testing while taking medicines for osteoporosis/osteopenia.

ICD-10-CM Codes that Support Medical Necessity
Effective for dates of service on or after 01/04/2018, the FDA has approved denosumab (Xgeva®) for the treatment of skeletal-related events in patients with multiple myeloma. ICD-10-CM code E83. 52 should be used to report management of hypercalcemia of malignancy.

Full Answer

What is Prolia for osteoporosis?

• Prolia is the first and only prescription medicine for postmenopausal osteoporosis that is a shot given 2 times a year in your doctor’s office You should take calcium and vitamin D as your doctor tells you to while you receive Prolia For dates of service 01/01/2 012 and forward :

What is the ICD 10 code for osteoporosis?

ICD-10-CM Diagnosis Code Z87.310 "Includes" further defines, or give examples of, the content of the code or category. A pathologic bone fracture due to osteoporosis. It is generally caused by a fall from a standing height or lower and usually involves the spine, hip, or wrist.

Is denosumab (Prolia) effective for osteoporosis?

They concluded that “Denosumab (Prolia) [in 60 mg doses] could be an effective dose for Japanese postmenopausal women with osteoporosis, as was shown in the Caucasian population.” Prolia treatment increases bone density but there is no evidence that it influences bone quality.

When should Prolia be discontinued for bone preservation?

Women who are treated for breast cancer via adjuvant AI (aromatase inhibitors) therapy often take Prolia for bone preservation reasons. When the AI therapy terminates, Prolia is supposed to be discontinued. Some physicians discontinue Prolia when the patient achieves the target T-Score that places them outside the osteoporosis category.

What is the ICD 10 code for long term use of Prolia?

Long term (current) use of bisphosphonates Z79. 83 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM Z79. 83 became effective on October 1, 2021.

What is the diagnosis code for Prolia?

† Diagnosis code Z79. 818 may be used for males receiving androgen deprivation therapy (eg, leuprolide acetate or goserelin acetate) for prostate cancer.

Can you take Prolia long term?

No, there isn't a set number of years you can take Prolia. In studies, people have safely taken Prolia for up to 8 years. If the drug is working to improve your condition, your doctor may have you take it long term.

How is J0897 billed?

HCPCS code J0897 is defined as 1 mg. Providers should report 1 unit for each 1 mg dose provided during the billing period. Drugs that have the ingredients romosozumab-aqqg are billed using HCPCS code J3111, if all existing guidelines for coverage under the home health benefit are met.

What is the ICD 10 code for Prolia Injection?

ICD-10-CM Codes that Support Medical Necessity Effective for dates of service on or after 01/04/2018, the FDA has approved denosumab (Xgeva®) for the treatment of skeletal-related events in patients with multiple myeloma. ICD-10-CM code E83. 52 should be used to report management of hypercalcemia of malignancy.

What is the ICD 10 code for osteoporosis?

0 – Age-Related Osteoporosis without Current Pathological Fracture. ICD-Code M81. 0 is a billable ICD-10 code used for healthcare diagnosis reimbursement of Age-Related Osteoporosis without Current Pathological Fracture.

How long should Prolia be continued?

Even though the maximum follow-up time for published clinical data on the long-term effects of denosumab treatment is 10 years, there is no absolute limit on treatment duration [31]. In some patients at continued high risk for fracture, treatment with denosumab should be continued indefinitely.

Is Prolia covered by Medicare Part B or Part D?

For those who meet the criteria prescribed above, Medicare Part B covers Prolia. If you don't meet the above criteria, your Medicare Part D plan may cover the drug. GoodRx reports that 98% of surveyed Medicare prescription plans cover Prolia. With Medicare Part D coverage, you're likely to pay coinsurance or a copay.

Does Prolia have to be given exactly every 6 months?

Prolia is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation.

How is Prolia billed to Medicare?

The majority of commercial and Medicare plans cover Prolia®. The list price for Prolia® is $1,434.14* ,† per treatment every six months.

What is Prolia Injection?

Denosumab injection (Prolia) is used treat osteoporosis that is caused by corticosteroid medications in men and women who will be taking corticosteroid medications for at least 6 months and have an increased risk for fractures or who cannot take or did not respond to other medication treatments for osteoporosis.

What drug class is Prolia?

Prolia belongs to a class of drugs called Antineoplastics, Monoclonal Antibody; Monoclonal Antibodies, Endocrine.

What is the Z79.02?

Z79.02 Long term (current) use of antithrombotics/antiplatelets. Z79.1 Long term (current) use of non-steroidal anti-inflammatories (NSAID) Z79.2 Long term (current) use of antibiotics. Z79.3 Long term (current) use of hormonal contraceptives. Z79.4 Long term (current) use of insulin.

What is the ICd 10 code for drug abuse?

Long term (current) drug therapy Z79- 1 drug abuse and dependence (#N#ICD-10-CM Diagnosis Code F11#N#Opioid related disorders#N#2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code#N#F11 -#N#ICD-10-CM Diagnosis Code F19#N#Other psychoactive substance related disorders#N#2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code#N#Includes#N#polysubstance drug use (indiscriminate drug use)#N#F19) 2 drug use complicating pregnancy, childbirth, and the puerperium (#N#ICD-10-CM Diagnosis Code O99.32#N#Drug use complicating pregnancy, childbirth, and the puerperium#N#2016 2017 2018 2019 2020 2021 Non-Billable/Non-Specific Code#N#Use Additional#N#code (s) from F11 - F16 and F18 - F19 to identify manifestations of the drug use#N#O99.32-)

What are the effects of prolia and bisphosphonates on osteoclasts?

Effect on Osteoclast Cells. First, Prolia and bisphosphonates differ in how they affect osteoclast cells. Osteoclast cells are the cleaners of old bone. The newly formed osteoclast cells join mature osteoclasts to perform an important role: the breakdown of the old bone.

How long does Prolia last?

According to Dr. Adachi, in the rare cases when they occur, Prolia side effects last up to three months . They do not persist for more than five months (the length of time Prolia is in your body). In general, the vast majority of Prolia side effects are resolved within three months.

How long does it take for Prolia to cause a rash?

Atypical femoral fractures occur when Prolia use is greater than 5 years.

How long does prolia stay in the body?

Prolia is in the body for approximately five months, whereas bisphosphonates can linger in the body for several years.

What is Prolia monoclonal antibody?

Kent McLeod, pharmacist and owner of NutriChem Pharmacy, defines Prolia as an immunoglobulin monoclonal antibody — a glycoprotein that interferes with the protein RANK ligand (RANKL) and prevents the formation, maturation and survival rates of osteoclasts. RANKL is the molecule blocked by denosumab.

What happens when bisphosphonates bind to osteoclasts?

When they bind to these cells, this leads to the death of the osteoclasts cells and thus stops bone breakdown. Bisphosphonates, on the other hand, reduce osteoclast activity. This, in turn, leads to a slowdown in the turnover of bone and removal of old bone. Differences Between Bisphosphonates and Prolia.

Can prolia be treated?

Prolia need not be the treatment of choice if your diagnosis places you in a low or moderate fracture risk category. The right combination of exercise and good nutrition can help you to stay (or move you into) the low risk fracture risk category.

How does Prolia work?

Prolia works by targeting a molecule that the bone-removing cells need in order to work. Important Safety Information.

Where to administer Prolia?

Administer Denosumab (Prolia™) via subcutaneous injection in the upper arm, the upper. thigh, or the abdomen. Denosumab (Prolia™) is supplied in a single-use prefilled syringe with a safety guard or in a single-use vial.

Is Prolia approved for multiple myeloma?

Limitations: • Denosumab (PROLIA™) is contraindicated in patients with hypocalcemia. • Denosumab (PROLIA™) is contraindicated in patients with pregnancy. • Denosumab (Xgeva™) is not approved for patients with multiple myeloma or other cancers of the blood. Coding Guidelines:

Is denosumab approved by Medicare?

The FDA has approved the use of denosumab (PROLIA™) and (Xgeva™). Medicare has determined under Section 1861 (t) that this drug may be paid when it is administered incident to a physician’s service and is determined to be reasonable and necessary.

Does Prolia help with bone loss?

Prolia has helped stop most of the bone-removing cells from getting to the bone and causing bone loss. Why Prolia is different. • Prolia is the first and only prescription medicine for postmenopausal osteoporosis that is a shot given 2 times a year in your doctor’s office.

Official Answer

There are no recommendations for how long you should take Prolia injections.

Does taking Prolia Injections longer improve my fracture risk?

Prolia reduces the number of new vertebral fracture in postmenopausal women and the longer it is taken shows there is a bigger decrease in chance of vertibral fracture.

When should I stop Prolia?

It is important that you should NOT stop Prolia without discussing this with your healthcare professional.