icd 10 code for methylmalonic

Methylmalonic acidemia. E71.120 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2019 edition of ICD-10-CM E71.120 became effective on October 1, 2018.

Full Answer

What is the ICD 10 code for methylmalonic acidemia?

Methylmalonic acidemia. E71.120 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2019 edition of ICD-10-CM E71.120 became effective on October 1, 2018.

What is the ICD 10 code for excluded note?

E53.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM E53.8 became effective on October 1, 2021. This is the American ICD-10-CM version of E53.8 - other international versions of ICD-10 E53.8 may differ. A type 1 excludes note is a pure excludes.

What is the ICD 10 code for genetic carrier of other disease?

Genetic carrier of other disease. Z14.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What is methylmalonic acidemia?

The methylmalonic acidemias are organic acidemias caused by an enzymatic defect in the metabolism of four amino acids (methionine, threonine, isoleucine and valine). This results in an abnormally high level of acid in the blood (academia) and body tissues. In the acute form, drowsiness, coma, and seizures may occur.

What is MMA metabolic disorder?

Methylmalonic acidemia (MMA) is an inherited condition caused by a faulty gene. Children with MMA lack a protein that the body needs to break down fats and cholesterol inside cells. As a result, these substances build up in cells, causing damage to the brain, liver, kidneys, and other organs that gets worse over time.

How is MMA diagnosed?

Determination of organic acids in urine and the acylcarnitine profile in blood are the most commonly used investigations to detect MMA and PA. Determination of amino acid concentrations may help in diagnosis and treatment.

How do you get methylmalonic acidemia?

Methylmalonic acidemia can be caused by mutations (or mistakes) in several genes. Individuals with methylmalonic acidemia can be divided into two groups: 1) patients with isolated MMA, where only methylmalonic acid is elevated 2) patients with combined defects who also have increased levels of homocysteine.

Is MMA a urea cycle disorder?

Hyperammonemia that is caused by PA or MMA is called secondary hyperammonemia since the enzyme deficiencies that cause the disorders are not part of the urea cycle.

What does MMA stand for in medical terms?

MANAGED MEDICAL ASSISTANCE (MMA) PROGRAM Section I.

Is methylmalonic acid the same as B12?

The methylmalonic acid (MMA) test may be used to help diagnose an early or mild vitamin B12 deficiency. It may be ordered by itself but generally with a homocysteine test as a follow-up to a vitamin B12 test result that is in the lower end of the normal range.

What is the CPT code for methylmalonic acid?

LOINC MapOrder CodeOrder Code NameOrder Loinc706961Methylmalonic Acid, Serum13964-2

What is MMA and homocysteine?

Serum homocysteine and methylmalonic acid (MMA) levels are helpful confirmatory tests for cobalamin and folate deficiencies. Both are increased in cobalamine deficiency. Homocysteine but not MMA is increased in folate deficiency.

What causes high levels of methylmalonic acid?

High levels of methylmalonic acid in the blood may also be an indication of kidney disease. Kidney disease is often identified through the use of other blood and diagnostic tests. Damage to the kidneys can prevent the filtering of methylmalonic acid from the blood.

What are the symptoms of methylmalonic acidemia?

Symptoms of a decompensation event include poor feeding, vomiting, trouble breathing, and lack of energy (lethargy). These can occur at different ages and can range from mild to severe. Methylmalonic acidemia is caused by changes in several different genes and is inherited in an autosomal recessive fashion.

What is malonic and methylmalonic aciduria?

Combined malonic and methylmalonic aciduria (CMAMMA) is a condition characterized by high levels of certain chemicals, known as malonic acid and methylmalonic acid, in the body. A distinguishing feature of this condition is higher levels of methylmalonic acid than malonic acid in the urine, although both are elevated.

What is the treatment for MMA?

Treatment consists of cobalamin and carnitine supplements and a low-protein diet. The child's diet must be carefully controlled. If supplements do not help, the health care provider may also recommend a diet that avoids substances called isoleucine, threonine, methionine, and valine.

Is methylmalonic acidemia fatal?

Methylmalonic acidemia (MMA) is a rare and potentially fatal genetic disorder that affects metabolism and multiple body systems that affects about one in 100,000 infants. It's caused by a genetic defect that prevents the body from properly processing certain proteins.

Is there a cure for MMA?

"MMA is very rare. There is no cure but the doctors are getting better at managing it. Previously, there was little knowledge in terms of management, so there aren't very many old people with it.

How can MMA levels be reduced?

A dose of 1,000 microg/day proved to be the most effective in lowering MMA levels to within normal limits. Serum tHcy was normalized in six of 11 subjects who had elevated tHcy pretreatment with oral Cbl alone and in one subject in combination with a multivitamin.