Mitochondrial metabolism disorder, unspecified. E88.40 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2019 edition of ICD-10-CM E88.40 became effective on October 1, 2018.
E88.40 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2020 edition of ICD-10-CM E88.40 became effective on October 1, 2019.
G71.3 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM G71.3 became effective on October 1, 2021. This is the American ICD-10-CM version of G71.3 - other international versions of ICD-10 G71.3 may differ. A type 1 excludes note is a pure excludes.
Mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (MELAS syndrome) 277.87 MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes) 277.87 ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions.
Mitochondrial diseases are a group of metabolic disorders. Mitochondria are small structures that produce energy in almost all of your cells. They make it by combining oxygen with the fuel molecules (sugars and fats) that come from your food. When the mitochondria are defective, the cells do not have enough energy.
ICD-10 code: G71. 3 Mitochondrial myopathy, not elsewhere classified.
The symptoms of mitochondrial myopathies include muscle weakness or exercise intolerance, heart failure or rhythm disturbances, dementia, movement disorders, stroke-like episodes, deafness, blindness, droopy eyelids, limited mobility of the eyes, vomiting, and seizures.
How are mitochondrial diseases diagnosed?A review of a patient's family history.A complete physical examination.A neurological examination.A metabolic examination that includes blood and urine tests, and, if needed, a cerebral spinal fluid test (spinal tap).
Mitochondrial disease can cause a vast array of health concerns, including fatigue, weakness, metabolic strokes, seizures, cardiomyopathy, arrhythmias, developmental or cognitive disabilities, diabetes mellitus, impairment of hearing, vision, growth, liver, gastrointestinal, or kidney function, and more.
Mitochondrial cytopathies represent a heterogeneous group of multisystem disorders which preferentially affect the muscle and nervous systems. They are caused either by mutations in the maternally inherited mitochondrial genome, or by nuclear DNA-mutations.
There are nine main forms of mitochondrial myopathy: Kearns-Sayre syndrome (KSS) Leigh syndrome. Mitochondrial DNA (mtDNA) depletion syndrome.
Common clinical features of mitochondrial disorders include ptosis, external ophthalmoplegia, proximal myopathy and exercise intolerance, cardiomyopathy, sensorineural deafness, optic atrophy, pigmentary retinopathy, and diabetes mellitus.
Primary mitochondrial myopathies (PMM) are a group of disorders that are associated with changes in genetic material (e.g. depletions, deletions, or mutations) found within the DNA of mitochondria (mtDNA) or with genes outside the mitochondria (nuclear DNA), affecting predominantly the skeletal muscle.
What causes mitochondrial dysfunction? On a physiological level, mitochondrial dysfunction is caused by exposure to certain environmental factors (such as certain pharmaceutical drugs, occupational chemicals and cigarette smoke) or genetic abnormalities (of both mitochondrial and nuclear DNA).
Mitochondrial diseases are not contagious, and they are not caused by anything a person does. They're caused by mutations, or changes, in genes — the cells' blueprints for making proteins.
For a specific clinical syndrome, a non-invasive genetic test might be possible on blood, urine or buccal mucosa. However, if these tests return negative, or the clinical features in the first instance necessitate a muscle biopsy (eg CPEO), then this is most commonly undertaken.
Typically, the age of death is between 10 to 35 years, although some patients may live longer. Death may come as a result of general body wasting due to progressive dementia and muscle weakness, or complications from other affected organs such as heart or kidneys.
What are the symptoms of myopathy?Muscle weakness, most commonly of your upper arms and shoulders and thighs (more common and more severe).Muscle cramps, stiffness and spasms.Fatigue with exertion.Lack of energy.
Chronic pain is common in patients with mitochondrial disease. Pain due to mitochondrial disease is primarily of neuropathic nature. Distribution, intensity and type of pain are genetically determined.
Together, Leigh syndrome and MELAS are the most common mitochondrial myopathies. The prognosis of Leigh syndrome is generally poor, with survival generally being a matter of months after disease onset.
Type-1 Excludes mean the conditions excluded are mutually exclusive and should never be coded together. Excludes 1 means "do not code here."
The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code E88.4. Click on any term below to browse the alphabetical index.