Overview. Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an abnormal protein — known as monoclonal protein or M protein — is in your blood. This abnormal protein is formed within your bone marrow, the soft, blood-producing tissue that fills in the center of most of your bones.Jul 22, 2021
D47.2ICD-10 | Monoclonal gammopathy (D47. 2)
273.1273.1 - Monoclonal paraproteinemia | ICD-10-CM.
A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Up to 25% of cases of monoclonal gammopathy of undetermined significance (mgus) progress to a b-cell malignancy or myeloma.
How are monoclonal gammopathies diagnosed? Once abnormal proteins are found in the blood, more testing is needed. A blood screening and sometimes a urine screening is recommended. This is often done with a lab test called electrophoresis.
Monoclonal gammopathies are conditions in which abnormal proteins are found in the blood. The most common condition linked with these abnormal proteins is monoclonal gammopathy of undetermined significance (MGUS). MGUS causes no symptoms. Diagnosis is often done with a lab test called electrophoresis.
Treatment. MGUS doesn't require treatment. But your doctor is likely to recommend periodic checkups to monitor your health, probably starting six months after your diagnosis.Jul 22, 2021
D89.00.
Abstract. Monoclonal gammopathy is a group of B-cell disorders which result in the production of a specific and unique monoclonal immunoglobulin (M-component). Biclonal gammopathy is characterized by the simultaneous appearance of two different M-components. The incidence is about 1% of all monoclonal gammopathy.
Immunoglobulin (Ig) M monoclonal gammopathy of undetermined significance (IgM-MGUS) is defined as a serum IgM monoclonal protein < 3 g/dL, bone marrow lymphoplasmacytic infiltration < 10%, and no evidence of constitutional symptoms, anemia, hyperviscosity, lymphadenopathy, or hepatosplenomegaly related to the ...
There are 3 subtypes of MGUS, namely, immunoglobulin M (IgM) MGUS, non-IgM MGUS, and light-chain MGUS, each with distinct rate and type of progression (Table 1).
Multiple myeloma Without00: Multiple myeloma Without mention of complete remission.
This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code D47.2 and a single ICD9 code, 273.1 is an approximate match for comparison and conversion purposes.
Monoclonal gammopathy of undetermined significance (MGUS, unknown or uncertain may be substituted for undetermined), formerly benign monoclonal gammopathy, is a condition in which a paraprotein is found in the blood during standard laboratory blood tests.
There are various kinds of defense cells (immune cells) in the body. Specific immune cells produce antibodies in the blood. The antibodies stick to pathogens and foreign substances in the blood, for example. This allows the antibodies to make the pathogens and foreign substances visible to the immune system.
This information is not intended for self-diagnosis and does not replace professional medical advice from a doctor.
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The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D47.2:
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code (s). The following references for the code D47.2 are found in the index:
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE-. conditions characterized by the presence of m protein monoclonal protein in serum or urine without clinical manifestations of plasma cell dyscrasia. PARAPROTEINEMIAS-.
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D47.2 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.
Patients with IgM MGUS lack the signs and symptoms of an overt lymphoproliferative disorder of plasma cell neoplasm, and the paraprotein is typically discovered incidentally on serum protein electrophoresis.
IgM monoclonal gammopathy of undetermined significance (MGUS) is defined by a serum IgM paraprotein concentration < 30 gram per liter; bone marrow lymph oplasmacytic infiltration of < 10%; and no evidence of anemia, constitutional symptom s, hyperviscosity, lymphadenopathy, hepatosplenomegaly, or other end-organ damage that can be attributed to the underlying lymphoproliferative disorder..
International Classification of Diseases for Oncology, Third Edition, Second Revision. Geneva: World Health Organization, 2020