icd 10 code for serum protein immuno fixation electrophosesis

Full Answer

What is the ICD 10 code for abnormal plasma protein?

Abnormality of plasma protein, unspecified. R77.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What is included in the special instructions for serum protein electrophoresis?

Quantitation of immunoglobulins IgA, IgG, and IgM; IFE interpretation of heavy- and light-chain patterns; serum protein electrophoresis Special Instructions State the patient's age and clinical diagnosis on the test request form.

What is the ICD 10 code for abnormal platelets and thrombocytes?

abnormalities of platelets and thrombocytes ( D69.-) Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

What are the abnormal levels of other serum enzymes?

Abnormal levels of other serum enzymes 1 Alkaline phosphatase raised. 2 Elevated alkaline phosphatase. 3 Elevated amylase. 4 Elevated cpk. 5 Hyperamylasemia. 6 ... (more items)

What ICD 10 code covers serum protein electrophoresis?

Abnormality of plasma protein, unspecified The 2022 edition of ICD-10-CM R77. 9 became effective on October 1, 2021. This is the American ICD-10-CM version of R77.

What is Immunofixation electrophoresis serum?

A serum immunofixation test measures specific proteins in your blood. It helps to identify certain illnesses that are otherwise hard to detect, such as multiple myeloma, a blood cancer. The test is also known as IFE, immunofixation electrophoresis, or protein electrophoresis.

What is the CPT code for immunofixation serum?

The MUEs for CPT code 86334 (Immunofixation electrophoresis) is changed from 1 to 2 units of service to allow multiple electrophoresis or immunofixation tests to be performed on the same specimen when monitoring multiple myeloma patients.

What is the difference between immunofixation and electrophoresis?

Urine protein electrophoresis (UPEP) is used to identify the presence of the Bence Jones protein in urine. Immunofixation is used to identify the subtype of protein (ie, IgA lambda).

What is the CPT code for immunoelectrophoresis serum?

001495: Immunofixation (IFE), Serum and Protein Electrophoresis, Serum | Labcorp.

Is immunofixation the same as immunoelectrophoresis?

Immunofixation electrophoresis (IFE) has largely replaced immunoelectrophoresis (IEP) for establishing the presence and isotype of a monoclonal immunoglobulin M-protein in serum and urine (Fig. 93.3). IFE is easier to perform, somewhat more sensitive, and easier to interpret than IEP.

What does a serum protein electrophoresis test for?

Serum protein electrophoresis is used to identify patients with multiple myeloma and other serum protein disorders. Electrophoresis separates proteins based on their physical properties, and the subsets of these proteins are used in interpreting the results.

What is procedure code 84155?

CPT® Code 84155 in section: Protein, total, except by refractometry.

What is procedure code 82784?

CPT® Code 82784 in section: Gammaglobulin (immunoglobulin)

When do you order serum protein electrophoresis?

Serum protein electrophoresis is generally considered in any patient with an elevated total protein, especially those with elevated globulin level relative to albumin, or any signs and symptoms suggestive of an underlying plasma cell disorder such as multiple myeloma, Waldenstrom's macroglobulinemia, or primary ...

What is a monoclonal protein serum blood test?

This test measures the total amount of immunoglobulin proteins in your blood. It is useful to follow if you are found to have a monoclonal protein in your blood or urine. An increasing amount of M protein over time is one of the criteria for treatment or a change in treatment.

What is the purpose of immunofixation?

Immunofixation permits the detection and typing of monoclonal antibodies or immunoglobulins in serum or urine. It is of great importance for the diagnosis and monitoring of certain blood related diseases such as myeloma.

Test Includes

Quantitation of serum immunoglobulins IgA, IgG, and IgM; IFE qualitative interpretation of heavy- and light-chain patterns; serum protein electrophoresis; quantitation of serum free κ and λ light chains plus κ:λ ratio

Expected Turnaround Time

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Collection

Sample should be allowed to clot and the serum separated as soon as possible to prevent hemolysis.

Methodology

Electrophoresis followed by immunodiffusion against monospecific antisera to immunoglobulin and individual heavy and light chains (IFE); protein electrophoresis on agarose media; turbidimetric quantitation of IgA, IgG, and IgM; turbidimetric quantitation of free κ and λ light chains

Additional Information

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines™) recommend the use of serum free light chain assays in the initial diagnostic work-up of multiple myeloma and related disorders.

Footnotes

1. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines™) for Multiple Myeloma, Version 1.2011. Fort Washington, Pa: NCCN; 2011.

Test Code

Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.

Clinical Significance

Protein, Total and Protein Electrophoresis with Immunofixation (IFE), Serum - Serum protein electrophoresis (SPE) is an analytical technique that provides separation of serum protein into six fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, and Gamma.

Test Resources

Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.