Sessile serrated lesion From Wikipedia, the free encyclopedia A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway.
A documented diagnosis of “sessile serrated polyp (SSP),” “sessile serrated adenoma (SSA)” or “sessile serrated lesion” without any further details is classified to benign neoplasms (D10–D36), per the ICD-10-CA alphabetical index lead term “Polyp, polypus,” subterm “adenomatous (see also Neoplasm, benign).”1
Colorectal epithelial lesion with serrated architecture and arises from serrated pathway ( BRAF or KRAS mutation) Include hyperplastic polyps, sessile serrated lesions, traditional serrated adenomas and serrated adenoma, unclassified
ICD-10-CM Diagnosis Code K63.9 Granuloma L92.9 ICD-10-CM Diagnosis Code L92.9 Melanosis L81.4 ICD-10-CM Diagnosis Code L81.4 Proctosigmoiditis K63.89 Rectosigmoiditis K63.89 ICD-10-CM Codes Adjacent To K63.89 Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. Sessile serrated lesion. Other names. Sessile serrated polyp (SSP)
Serrated polyps (serrated adenomas) have a saw-tooth appearance under the microscope. There are 2 types, which look a little different under the microscope: Sessile serrated adenomas (also called sessile serrated polyps) Traditional serrated adenomas.
The sessile serrated polyp (SSP), also known as sessile serrated adenoma, is the evil twin among the colorectal cancer precursors.
Benign neoplasm of colon, unspecified D12. 6 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D12. 6 became effective on October 1, 2021.
According to the World Health Organization (WHO) [14], serrated lesions are currently classified into three main categories as follows: (1) hyperplastic polyps (HPs), (2) sessile serrated adenoma/polyps (with or without dysplasia) (SSA/Ps), and (3) traditional serrated adenomas (TSAs).
Sessile serrated polyps have a more irregular surface, a pattern to the surface that has been called “cloudlike,” and indistinct edges compared with hyperplastic polyps. Sessile serrated polyps also have large open pits on the surface (type O pits) when viewed with magnification.
According to the latest World Health Organization (WHO) classification published in 2010 [21], serrated polyps are now categorized into three main subtypes: hyperplastic polyps, sessile serrated adenoma/polyps without or with cytological dysplasia, and traditional serrated adenomas.
Sessile polyps can be snared and removed somewhat easily in a colonoscopy, though larger ones are typically taken out in pieces. Pedunculated polyps hang from a stalk attached to your colon wall. (Think of a cherry on a stem.) They're easy to spot and can usually be removed in one piece during a colonoscopy.
They are hard to find on endoscopic examination and can turn into cancer somewhat quickly. Serrated adenomas (also called traditional serrated adenomas, or TSAs): These polyps are less common but have dysplasia (abnormal cells) and can progress to cancer.
Sessile serrated polyps were previously classified to K62. – Other diseases of anus and rectum and K63.
Sessile serrated adenoma/polyps (SSA/Ps) are early precursor lesions in the serrated neoplasia pathway, which results in colorectal carcinomas with BRAF mutations, methylation for DNA repair genes, a CpG island methylator phenotype, and high levels of microsatellite instability.
Z12. 11: Encounter for screening for malignant neoplasm of the colon.
Criteria for serrated polyposis syndrome include 1 of the following: At least 5 serrated polyps proximal to the sigmoid colon with at least 2 greater than 1 cm in size. Any serrated polyp proximal to the sigmoid colon in a patient with a first degree relative with serrated polyposis syndrome.
Definition / general. At least 5 serrated polyps proximal to the sigmoid colon with at least 2 greater than 1 cm in size. Any serrated polyp proximal to the sigmoid colon in a patient with a first degree relative with serrated polyposis syndrome.
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere.
The 2022 edition of ICD-10-CM D12.3 became effective on October 1, 2021.
Serrated polyposis syndrome. The serrated polyposis syndrome (SPS) is a relatively rare condition characterized by multiple and/or large serrated polyps of the colon. Serrated polyps include SSLs, hyperplastic polyps, and traditional serrated adenomas. Diagnosis of this disease is made by the fulfillment of any of the World Health Organization’s ...
History. Sessile serrated adenomas were first described in 1996. In 2019, the World Health Organization recommended the use of the term "sessile serrated lesion ," rather than sessile serrated polyp or adenoma.
SSLs are diagnosed by their microscopic appearance; histomorphologically, they are characterized by (1) basal dilation of the crypts, (2) basal crypt serration, (3) crypts that run horizontal to the basement membrane (horizontal crypts), and (4) crypt branching.
SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC gene . Multiple SSLs may be part of the serrated polyposis syndrome.
Treatment. Complete removal of a SSL is considered curative. Several SSLs confer a higher risk of subsequently finding colorectal cancer and warrant more frequent surveillance. The surveillance guidelines are the same as for other colonic adenomas.
Multiple SSLs may be part of the serrated polyposis syndrome.
The diagnosis of sessile serrated lesion is usually made after the adenoma is removed during a medical procedure called a colonoscopy. The sessile serrated lesion may be removed in one piece or in multiple pieces. The tissue sample is then sent to a pathologist for examination.
When cancer develops in a sessile serrated lesion, it usually starts in a pre-cancerous condition called dysplasia.
Hyperplastic polyps still occur and are common, but they tend to be found on the left side of the colon, as opposed to the right-sided location of most sessile serrated lesions.
Unfortunately, it is possible for gastroenterologists and surgeons to miss sessile serrated lesions when doing a colonoscopy as they can be very difficult to see. They can be flat and indistinct and may blend in with the surrounding lining of the colon.
All sessile serrated lesions require complete removal at colonoscopy but the presence of dysplasia may require a quicker repeat colonoscopy if the removal wasn’t complete on the first visit.