icd 10 code for spherocytosis

What is the ICD 10 code for hereditary spherocytosis?

Oct 01, 2021 · Hereditary spherocytosis. D58.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D58.0 became effective on October 1, 2021. This is the American ICD-10-CM version of D58.0 - other international versions of ICD-10 D58.0 may differ.

What is heredity spherocytosis?

2021/2022 ICD-10-CM Index > 'Spherocytosis'. Toggle navigation.

What is the ICD 10 code for Minkowski-Chauffard syndrome?

ICD-10-CM Diagnosis Code D58.0. Hereditary spherocytosis. 2016 2017 2018 2019 2020 2021 2022 Billable/Specific Code. Applicable To. Acholuric (familial) jaundice. Congenital (spherocytic) hemolytic icterus. Minkowski-Chauffard syndrome. ICD-10-CM Diagnosis Code Q12.4 [convert to ICD-9-CM] Spherophakia.

What is spherocytosis disease?

Collapse Section. Hereditary spherocytosis is a condition that affects red blood cells. People with this condition typically experience a shortage of red blood cells (anemia ), yellowing of the eyes and skin (jaundice), and an enlarged spleen (splenomegaly).

What type of anemia is spherocytosis?

Hereditary spherocytosis is a condition characterized by hemolytic anemia (when red blood cells are destroyed earlier than normal). Signs and symptoms can range from mild to severe and may include pale skin, fatigue, anemia , jaundice , gallstones, and/or enlargement of the spleen.

What causes spherocytosis?

Spherocytosis is one of the most common inherited hemolytic anemias. It is caused by a defect in the erythrocyte membrane, which leads to an increased permeability for sodium and water, giving the erythrocyte its typical spherical form.

How do you diagnose spherocytosis?

A blood draw will be done to get a complete blood count, an immature red blood cell (reticulocyte) count, and a look at the shape of red blood cells to look for spherocytes. It is also important to rule out autoimmune hemolytic anemia. This can be done with a direct antiglobulin test.

What type of mutation is spherocytosis?

About half of all cases of hereditary spherocytosis are due to mutations in the ANK1 gene. Other genes associated with the condition include the EPB42, SLC4A1, SPTA1, and SPTB genes.

Is spherocytosis an autoimmune disorder?

Spherocytosis may be present in autoimmune hemolytic anemia in which autoantibodies react with red blood cells and cause alterations in their membranes that includes lysis of red blood cells. Spherocytes may develop during this destruction of red blood cells.

What are Leptocytes?

Leptocytes (or wafer cells) are thin, flat cells with the hemoglobin at the periphery of the cell. Sickle cells (drepanocytes) are elongated, sometimes crescent-shaped, erythrocytes with pointed ends.

What is the significance of Schistocytes?

Schistocytes are split red blood cells that indicate microangiopathic hemolytic anemia. Their presence in a peripheral smear is the hallmark for diagnosing thrombotic thrombocytopenic purpura (TTP).Dec 3, 2015

What are the classic laboratory findings of hereditary spherocytosis?

The typical laboratory hallmark of hereditary spherocytosis, although not specific, is the presence of spherocytes on a peripheral blood smear, which are detectable in 97% of patients.

What is hereditary spherocytosis and explain its pathophysiology?

Hereditary spherocytosis (HS) is a familial hemolytic disorder associated with a variety of mutations that lead to defects in red blood cell (RBC) membrane proteins. [1, 2] It is also one of the most common causes of hemolytic anemia due to membrane defect.Feb 18, 2021

Is hereditary spherocytosis intravascular hemolysis?

Hemolysis may be an extravascular or an intravascular phenomenon. Autoimmune hemolytic anemia and hereditary spherocytosis are examples of extravascular hemolysis because the red blood cells are destroyed in the spleen and other reticuloendothelial tissues.Feb 19, 2022

Why does spherocytosis have increased MCHC?

This increased MCHC is a result of mild cellular dehydration. The mean cell volume (MCV) in patients with HS actually is low, presumably because of membrane loss and cell dehydration.Feb 18, 2021