icd 10 code for stenotrophomonas maltophilia infection

by Mr. Erich Wisoky IV 4 min read

Full Answer

What is the scientific name for Stenotrophomonas maltophilia?

Stenotrophomonas maltophilia has had multiple different names in the past. It was first found in a pleural effusion in 1943 and given the name Bacterium bookeri. It was then renamed to Pseudomonas maltophilia in 1961.

Which medications are used in the treatment of Stenotrophomonas maltophilia?

Cefiderocol is a new injectable siderophore cephalosporin that has shown promising data against carbapenem-resistant gram-negative bacteria, including Stenotrophomonas maltophilia. [93][94][95]  Eravacycline, omadacycline, and delafloxacin have demonstrated good in-vitro activity as well for their respective infection indications.

What is the pathophysiology of Stenotrophomonas maltophilia d457r?

Alonso A, Sanchez P, Martínez JL. Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance. Antimicrob Agents Chemother.

What is the mortality and morbidity of Stenotrophomonas infections?

Stenotrophomonas infections have been associated with high morbidity and mortality in severely immunocompromised and debilitated individuals.

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What is the ICD-10 code for stenotrophomonas?

B96. 89 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM B96. 89 became effective on October 1, 2021.

What is B96 89?

89 for Other specified bacterial agents as the cause of diseases classified elsewhere is a medical classification as listed by WHO under the range - Certain infectious and parasitic diseases .

What is the ICD-10 code for bacterial infection?

ICD-10 code: A49. 9 Bacterial infection, unspecified.

What is the diagnosis for ICD-10 code r50 9?

9: Fever, unspecified.

What is the ICD 10 code for gram-negative bacteria?

Gram-negative sepsis, unspecified A41. 50 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM A41. 50 became effective on October 1, 2021.

How do you code bacteremia in ICD-10?

ICD-10-CM Code for Bacteremia R78. 81.

Can B96 81 be used as a primary diagnosis?

The note in ICD-10 under codes B95-B97 states that 'these categories are provided for use as supplementary or additional codes to identify the infectious agent(s) in disease classified elsewhere', so you would not use B96. 81 as a primary diagnosis, but as an additional code with the disease listed first.

Can F07 81 be used as a primary diagnosis?

Our physicians have used IDC-10 code F07. 81 as the primary diagnosis for patients presenting with post concussion syndrome.

How do you code bacterial infections?

ICD-10 Code for Bacterial infection, unspecified- A49. 9- Codify by AAPC.

What is the diagnosis for ICD-10 code R06 2?

ICD-10 code R06. 2 for Wheezing is a medical classification as listed by WHO under the range - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified .

What is diagnosis code j06 9?

9 Acute upper respiratory infection, unspecified.

What is R53 81?

R53. 81: “R” codes are the family of codes related to "Symptoms, signs and other abnormal findings" - a bit of a catch-all category for "conditions not otherwise specified". R53. 81 is defined as chronic debility not specific to another diagnosis.

What is the ICD-10 code for Staphylococcus aureus?

ICD-10-CM Code for Staphylococcus aureus as the cause of diseases classified elsewhere B95. 6.

What is the ICD-10 code for ESBL UTI?

ICD-10 code Z16. 12 for Extended spectrum beta lactamase (ESBL) resistance is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .

What is the ICD-10 code for urinary retention?

ICD-10 code R33. 9 for Retention of urine, unspecified is a medical classification as listed by WHO under the range - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified .

What is the ICD-10 for UTI?

0 Urinary tract infection, site not specified.

What is Stenotrophomonas maltophilia?

Stenotrophomonas maltophilia is one of the less known drug-resistant bacteria that can cause challenging infections . This activity reviews the epidemiology of this organism as well as the risk factors of developing these infections. It also illustrates the pathophysiology and virulence factors of this pathogen and its relation with the clinical picture. It describes the modern evaluation and up-to-date treatment for the infections caused by this organism, as well as their estimated prognosis. Further, it highlights the role of the interprofessional team in case management.

When is treatment required for stenotrophomonas maltophilia?

Treatment with specific antibiotics is required when evidence for a true Stenotrophomonas maltophilia infection is established or in critically sick patients with a Stenotrophomonas maltophiliagrowth until further data are available. Treatment recommendations mostly come from in vitrostudies, retrospective studies, non-randomized clinical trials, and expert opinions. [64]

What is the second most common form of Stenotrophomonas maltophilia?

The second most common form of Stenotrophomonas maltophiliainfections is bacteremia, at 33% of the infections.[38]  Sometimes the bacteremia is polymicrobial, especially along with Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterococcus faecalis. [9][56] More than 70% of the reported cases were deemed to be central venous catheter-related infections. Recurrence has also been encountered in cases of retained central venous catheters or delayed targeted antibiotics [57].

What antibiotics are resistant to Stenotrophomonas maltophilia?

[42][43] It shows resistance to most beta-lactams through two inducible enzymes; the class B zinc-dependent penicillinase (L1) and the class A serine cephalosporinase (L2), rendering it resistant to ceftriaxone, piperacillin-tazobactam, and carbapenems. [4][18] Clavulanic acid has shown activity against the L2 enzyme but not L1.[9]  It also confers resistance to aminoglycosides by its aminoglycoside-modifying acetyl-transferase enzyme.[4]  Several other antimicrobial resistances are achieved through the efflux pumps (for example, the SmeDEF and SmeABC) that act on quinolones, aminoglycosides, macrolides, and tetracyclines. [4][18][42][44]

How long does it take to treat stentophilia?

The typical duration of antimicrobial courses for Stenotrophomonas maltophiliapneumonia is usually 7 days, which can be extended to 10 to 14 days in immunosuppressed patients. Bacteremia cases, on the other hand, are generally treated for 14 days total.

Is Stenotrophomonas maltophilia gram negative?

Stenotrophomonas maltophilia is a gram-negative bacillus, initially called Bacterium bookeri, when it was first identified in 1943 from a specimen of human pleural fluid.[1]  It was later classified as Pseudomonas maltophilia in 1961, then reassigned to the gammaproteobacteria class as Xanthomonas maltophilia in 1983, and eventually classified as a Stenotrophomonas in 199.[2][3][4] The name has Greek roots meaning “The narrow feeder - that loves malt.” The whole-genome sequence of representative isolate K279a genome sequence was published in 2008.[5][6]

Which nonfermenters are gram negative?

Other gram-negative non-fermenters like Pseudomonas aeruginosa, Acinetobacter baumannii, Achromobacter xylosoxidans, and Burkholderia cepacia-complex, can be misidentified as, co-exist with, or be responsible for similar infections to Stenotrophomonas maltophilia.

When was Stenotrophomonas maltophilia first found?

Stenotrophomonas maltophilia has had multiple different names in the past. It was first found in a pleural effusion in 1943 and given the name Bacterium bookeri. It was then renamed to Pseudomonas maltophilia in 1961. It was moved to the genus Xanthomonas in 1983, and most recently to Stenotrophomonas in 1993.

What is maltophilia pathogenesis?

S. maltophilia frequently colonizes humid surfaces such as the tubes used in mechanical ventilation and indwelling urinary catheters as well as medical devices such as suction catheters and endoscopes. Infection is usually facilitated by the presence of prosthetic material (plastic or metal), and the most effective treatment is ...

Why is S. maltophilia difficult to interpret?

The growth of S. maltophilia in microbiological cultures of respiratory or urinary specimens is difficult to interpret due to its low pathogenicity, and not a proof of infection.

What is the main pathogenic mechanism of S. maltophilia?

Deliberate induction of inflammatory responses is the main pathogenic mechanisms of S. maltophilia infection. S. maltophilia secretes outer membrane vesicles (OMVs), that cause an inflammatory response. OMVs from S. maltophilia ATCC 13637 were found to be cytotoxic to human lung epithelial cells.

Is maltophilia resistant to antibiotics?

S. maltophilia is naturally resistant to many broad-spectrum antibiotics (including all carbapenems) due to the production of two inducible chromosomal metallo-β-lactamases (designated L1 and L2). This makes treatment of infected patients very difficult.

Is maltophilia a cause of pneumonia?

In immunocompetent individuals, S. maltophilia is a relatively unusual cause of pneumonia, urinary tract infection, or bloodstream infection; in immunocompromised patients, however, S. maltophilia is a growing source of latent pulmonary infections. S. maltophilia colonization rates in individuals with cystic fibrosis have been increasing.

Can maltophilia cause nosocomial infections?

In immunocompromised patients, S. maltophilia can lead to nosocomial infections. It is also an emerging nosocomial pathogen associated with opportunistic infections in patients with cystic fibrosis, cancer, and HIV. Adherence of this organism to abiotic surfaces such as medical implants and catheters represents a major risk for hospitalized ...

How to diagnose S. maltophilia?

A culture of body fluids, such a blood, urine, sputum, or abdominal fluid, is used to confirm the specific type of bacteria. A consultation with an infectious disease specialist is important to differentiate bacterial colonization (where the bacteria are found in the body but do not cause symptoms) from an infection and to determine the best treatment options. [8465] [8466]

What is maltophilia infection?

Stenotrophomonas maltophilia (S. maltophilia) infection is a type of bacterial infection. S. maltophilia is found mostly in wet environments. In the hospital setting, S. maltophilia can be found in fluids, such as irrigation solutions (fluids used to clean a wound or wash out a body cavity like the ear canal or bladder) and intravenous (IV) fluids, as well as patient secretions, such as mucus from the respiratory tract and urine. The bacteria causes problems mainly in people who have a weakened immune system. [8465] [8466] [11611] To cause infections in healthy people, S maltophilia must bypass the normal human defenses, as can happen with the use of certain medical devices, such as catheters or IV lines. People who are hospitalized and receiving treatment for other serious medical conditions may be more susceptible to an infection, especially if their immune system is weakened. Symptoms vary depending on the area of the body infected. [8465] [8466]

Can maltophilia cause infections?

[8465] [8466] [11611] To cause infections in healthy people, S maltophilia must bypass the normal human defenses, as can happen with the use of certain medical devices, such as catheters or IV lines.

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