icd-10 code for thrombotic thrombocytopenic purpura

What is the ICD 10 code for Nonthrombocytopenic purpura?

Other nonthrombocytopenic purpura. D69.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2018/2019 edition of ICD-10-CM D69.2 became effective on October 1, 2018. This is the American ICD-10-CM version of D69.2 - other international versions of ICD-10 D69.2 may differ.

What are the clinical features of thrombocytopenic purpura?

Clinical features include thrombocytopenia; hemolytic anemia; azotemia; fever; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as renal failure.

What is the ICD 10 code for Acquired thrombocytopenia?

Acquired thrombocytopenia; Thrombocytopenia (low blood platelets); Thrombocytopenic disorder ICD-10-CM Diagnosis Code D69.2 [convert to ICD-9-CM]

What is the ICD 10 code for thrombotic microangiopathy?

Thrombotic microangiopathy. M31.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What is a thrombotic thrombocytopenic purpura?

What is it? TTP is a rare, life-threatening blood disorder. In TTP, blood clots form in small blood vessels throughout your body. The clots can limit or block the flow of blood to your organs, such as your brain, kidneys, and heart. This can prevent your organs from working properly and can damage your organs.

What is the ICD-10-CM code for purpura?

Purpura and other hemorrhagic conditions The 2022 edition of ICD-10-CM D69 became effective on October 1, 2021. This is the American ICD-10-CM version of D69 - other international versions of ICD-10 D69 may differ.

Is thrombocytopenia the same as TTP?

TTP is also a disorder that is characterized by thrombocytopenia, but TTP includes microangiopathic hemolytic anemia (MAHA) in addition to severe thrombocytopenia.

What is the ICD-10 code for acute ITP?

ICD-10 | Immune thrombocytopenic purpura (D69. 3)

How is thrombotic thrombocytopenic purpura diagnosis?

Diagnostic tests used to confirm thrombotic thrombocytopenic purpura may include: Complete blood count (CBC). A CBC measures the number of platelets as well as the number of red blood cells and white blood cells. People with TTP have a lower number of red blood cells and platelets.

What is the difference between thrombocytopenia and ITP?

A healthy person usually has a platelet count of 150,000 to 400,000. You have thrombocytopenia if your number falls under 150,000. If you're wondering what the long name means, here's how it breaks down: "Thrombocytes" are your platelets, and "penia" means you don't have enough of something.

What is considered severe thrombocytopenia?

Degrees of thrombocytopenia can be further subdivided into mild (platelet count 100,000 to 150,000/microL), moderate (50,000 to 99,000/microL), and severe (<50,000/microL) [1].

What is the difference between primary and secondary thrombocytopenia?

The ITP Syndrome ITP is an autoimmune bleeding disorder caused by various etiologies, which is characterized by increased platelet destruction and impaired production, resulting in a decreased platelet count. Primary ITP is idiopathic, whereas secondary ITP is linked to an underlying condition (1).

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Epidemiology

The prevalence of thrombotic thrombocytopenic purpura (including both acquired and congenital forms) is difficult to determine. Worldwide, the incidence for iTTP ranges from 1/165,000-1,000,000 and, in France the prevalence is estimated at 1/77,000. The prevalence of cTTP ranges from 1/ 60,000-2,500,000.

Clinical description

iTTP generally occurs in adulthood, whereas cTTP usually in the neonatal period, during childhood or in the setting of pregnancy. Onset is usually acute but early symptoms may include fatigue, purpura or ecchymoses, abdominal pain, arthralgia and myalgia, resembling a flu-like episode.

Etiology

TTP is caused by a severely decreased activity (< 10%) of ADAMTS13, a metalloprotease involved in the cleavage of ultra-large von Willebrand factor multimers.

Diagnostic methods

First, the diagnosis of TMA must be evoked in a patient with MAHA and a negative direct antiglobulin test, associated with a peripheral thrombocytopenia, especially if there is an associated organ failure (cerebral, renal or cardiac involvement, abdominal pain). Once the diagnosis of TMA is made, TTP must be recognized.

Differential diagnosis

Differential diagnosis includes other TMAs (hemolytic uremic syndrome, TMA secondary to transplantation, chemotherapy, drug, HIV/AIDS, as well as HELLP syndrome) and other diseases including catastrophic antiphospholipid syndrome, severe sepsis, vitamin B12 deficiency, malignant hypertension and severe disseminated intravascular coagulopathy.

Genetic counseling

cTTP is inherited autosomal recessively and genetic counseling is suggested. The risk of inheriting the disease is 25% where both parents are unaffected carriers.