icd 9 code for digeorge syndrome

What is Digeorge syndrome?

Digeorge syndrome is considered by some researchers as a developmental field defect consisting of several casually distinct disorders, rather than a distinct syndromic entity. Conditions associated with the development of digeorge syndrome include diabetic embryopathy, fetal alcohol syndrome, and zellweger syndrome.

What is congenital anomaly?

A congenital anomaly characterized by immunodeficiency, abnormal facies, congenital heart disease, hypocalcemia, and increased susceptibility to infections. Pathologic characteristics include conotruncal abnormalities and absence or hypoplasia of thymus and parathyroid glands.

The ICD code D821 is used to code DiGeorge syndrome

DiGeorge syndrome is also known as 22q11.2 deletion syndrome,DiGeorge anomaly, velocardiofacial syndrome (VCFS), Shprintzen syndrome, conotruncal anomaly face syndrome (CTAF) or Takao syndrome, Sedlackova syndrome, Cayler cardiofacial syndrome, Strong syndrome, congenital thymic aplasia, and thymic hypoplasia.

Coding Notes for D82.1 Info for medical coders on how to properly use this ICD-10 code

Inclusion Terms are a list of concepts for which a specific code is used. The list of Inclusion Terms is useful for determining the correct code in some cases, but the list is not necessarily exhaustive.

MS-DRG Mapping

DRG Group #808-810 - Major hematol or immun diagnoses except sickle cell crisis and coagul with MCC.

ICD-10-CM Alphabetical Index References for 'D82.1 - Di George's syndrome'

The ICD-10-CM Alphabetical Index links the below-listed medical terms to the ICD code D82.1. Click on any term below to browse the alphabetical index.

Equivalent ICD-9 Code GENERAL EQUIVALENCE MAPPINGS (GEM)

This is the official exact match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that in all cases where the ICD9 code 279.11 was previously used, D82.1 is the appropriate modern ICD10 code.

What is the frequency of DiGeorge syndrome?

Depends on the specific symptoms. Frequency. 1 in 4,000. DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is a syndrome caused by the deletion of a small segment of chromosome 22.

How many people have DiGeorge syndrome?

With treatment, life expectancy may be normal. DiGeorge syndrome occurs in about 1 in 4,000 people. The syndrome was first described in 1968 by American physician Angelo DiGeorge. In late 1981, the underlying genetics were determined.

What are the articulation errors in children?

Compensatory articulation errors made by this population of children include: glottal stops, nasal substitutions, pharyngeal fricatives, linguapalatal sibilants, reduced pressure on consonant sounds, or a combination of these symptoms.

What are the problems with 22q11.2DS?

Common problems include hypernasality, language delays, and speech sound errors.

What are the symptoms of a ventricular septal defect?

Individuals can have many possible features, ranging in number of associated features and from the mild to the very serious. Symptoms shown to be common include: 1 Congenital heart disease (40% of individuals), particularly conotruncal malformations ( interrupted aortic arch (50%), persistent truncus arteriosus (34%), tetralogy of Fallot, and ventricular septal defect) 2 Cyanosis (bluish skin due to poor circulation of oxygen-rich blood) 3 Palatal abnormalities (50%), particularly velopharyngeal incompetence, submucosal cleft palate, and cleft palate; characteristic facial features (present in the majority of Caucasian individuals) including hypertelorism 4 Learning difficulties (90%), including cognitive deficits, attention deficit disorders 5 Hypocalcemia (50%) (due to hypoparathyroidism) 6 Significant feeding problems (30%) 7 Renal anomalies (37%) 8 Hearing loss (both conductive and sensorineural) ( hearing loss with craniofacial syndromes) 9 Laryngotracheoesophageal anomalies 10 Growth hormone deficiency 11 Autoimmune disorders 12 Immune disorders due to reduced T cell numbers 13 Schizophrenia 14 Seizures (with or without hypocalcemia) 15 Skeletal abnormalities 16 Psychiatric disorders

Is DiGeorge syndrome a neuropsychological disorder?

Children with DiGeorge syndrome have a specific profile in neuropsychological tests. They usually have a below-borderline normal IQ, with most individuals having higher scores in the verbal than the nonverbal domains. Some are able to attend normal schools, while others are home-schooled or in special classes. The severity of hypocalcemia early in childhood is associated with autism-like behavioral difficulties.

Is 22q11.2DS associated with Parkinson's disease?

22q11.2DS has been associated with a higher risk of early onset Parkinson's disease (PD). The neuropathology seen is similar to LRRK2 -associated PD. None of the genes affected in individuals with 22q11.2DS have previously been linked to PD but there are a number that are likely candidates. These include DGCR8 which is important for biogenesis of brain microDNA, SRPT5 which encodes a protein that interacts with the PARK2 protein, COMT which is involved in regulating dopamine levels, and microRNA miR-185 which is thought to target known PD loci LRRK2.