Condition:1 | Glucose-6-phosphate dehydrogenase defici ... |
Abbreviation:1 | G6PD |
Category:2 | Other |
SNOMED CT Code:3 | 62403005—Glucose-6-phosphate dehydrogena ... |
ICD-9-CM Code:5 | 282.2—Anemias due to disorders of glutat ... |
Condition:1 | Glucose-6-phosphate dehydrogenase deficiency |
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ICD-9-CM Code:5 | 282.2—Anemias due to disorders of glutathione metabolism |
ICD-10-CM Code:6 | D55.0—Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency |
Feb 01, 2012 · What is the correct ICD-9 code to use for G6PD (Glucose-6-phosphate dehydrogenase deficiency)? Using deficiency as the main term in the ICD-9 CM index , there is a subterm Glucose-6-phosphate dehydrogenase anemia , code 282.2. anemias due to disorders of glutathione metabolism.
Free, official information about 2012 (and also 2013-2015) ICD-9-CM diagnosis code 282.2, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion. ... G6PD deficiency; Anemia, glutathione reductase deficiency; Drug …
6 rows · Sep 14, 2009 · D55.0 — Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency. Affected Protein ...
Oct 01, 2021 · Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia. 2020 - New Code 2021 2022 Billable/Specific Code. D75.A is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Short description: Glucose-6-phosphate dehydrgnse (G6PD) defic without anemia
An inherited disorder in which a person doesn't have enough of an enzyme called G6PD that helps red blood cells work the way they should. In G6PD deficiency, the red blood cells break down when the body is exposed to infection, severe stress, or certain drugs, chemicals, or foods.
Your doctor can diagnose G6PD deficiency by performing a simple blood test to check G6PD enzyme levels. Other diagnostic tests that may be done include a complete blood count, serum hemoglobin test, and a reticulocyte count. All these tests give information about the red blood cells in the body.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a condition in which red blood cells break down when the body is exposed to certain drugs or the stress of infection. It is hereditary, which means it is passed down in families.Feb 6, 2020
The following is a partial list of medications and chemicals that individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency should avoid:Acetanilid.Furazolidone.Isobutyl nitrite.Nalidixic acid.Naphthalene.Niridazole.Sulfa drugs.
Names and CodesCondition:1Glucose-6-phosphate dehydrogenase deficiencyICD-9-CM Code:5282.2—Anemias due to disorders of glutathione metabolismICD-10-CM Code:6D55.0—Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency3 more rows•Sep 14, 2009
However, deficiency of G6PD was found to be related to other autoimmune diseases.
TypesG6PD SubtypesDemographic FeaturesWHO ClassificationG6PD B (wild-type)Most commonNormalG6PD A+Reported in 20%-30% of African American and African Black individualsClass IVG6PD A-Reported in 10%-15% of African American and African Black individualsClass IIIG6PD KaipingReported in Asian individualsClass III5 more rows
G6PD (glucose-6-phosphate dehydrogenase) deficiency describes a shortage of an enzyme (chemical) found in the red blood cells. It is very common in certain racial groups, and scientists think there are about 400 million people in the world with G6PD deficiency.
G6PD deficiency is an X-linked recessive disorder, with an inheritance pattern similar to that of hemophilia and color blindness: males usually manifest the abnormality and females are carriers. Females may be symptomatic if they are homozygous or if inactivation of their normal X chromosome occurs.Jul 19, 2021
G6PD deficiency and COVID-19 vaccines Like routine vaccines, COVID-19 vaccines can be safely administered to people with G6PD deficiency.
Can I give my child paracetamol or ibuprofen? Yes – paracetamol and NSAIDS (Nonsteroidal anti-inflammatory drugs) are safe for children with G6PD deficiency.
The common over-the-counter treatments for fever, pain, nasal congestion and cough – acetaminophen (Tylenol), ibuprofen (Advil), pseudoephedrine (Sudafed), and guaifenesin, (Robitussin) – are usually safe at normal therapeutic doses for people with G6PD deficiency.
References. Glucose-6-phosphate dehydrogenase deficiency, the most common enzyme deficiency worldwide, causes a spectrum of disease including neonatal hyperbilirubinemia, acute hemolysis, and chronic hemolysis. Persons with this condition also may be asymptomatic.
G6PD deficiency occurs with increased frequency throughout Africa, Asia, the Mediterranean, and the Middle East. In the United States, black males are most commonly affected, with a prevalence of approximately 10 percent.
Prevalence of the defici ency is correlated with the geographic distribution of malaria, which has led to the theory that carriers of G6PD deficiency may incur partial protection against malarial infection. 1 – 3 Cases of sporadic gene mutation occur in all populations.
Because acute hemolysis is caused by exposure to an oxidative stressor in the form of an infection, oxidative drug, or fava beans, treatment is geared toward avoidance of these and other stressors.
G6PD deficiency is one of a group of congenital hemolytic anemias, and its diagnosis should be considered in children with a family history of jaundice, anemia, splenomegaly, or cholelithiasis, especially in those of Mediterranean or African ancestry. 13.
Acute hemolysis is caused by infection, ingestion of fava beans, or exposure to an oxidative drug. 3 Medications that should be avoided in patients with G6PD deficiency are listed in Table 3, 6 and drugs that can be used safely in these patients are listed in Table 4. 6 Hemolysis occurs after exposure to the stressor but does not continue despite continued infection or ingestion. This is thought to be a result of older erythrocytes having the greatest enzyme deficiency and undergoing hemolysis first. Once the population of deficient erythrocytes has been hemolyzed, younger erythrocytes and reticulocytes that typically have higher levels of enzyme activity are able to sustain the oxidative damage without hemolysis. 7 Clinically, acute hemolysis can cause back or abdominal pain and jaundice secondary to a rise in unconjugated bilirubi n ( Table 5 21 ). Jaundice, in the setting of normal liver function, typically does not occur until greater than 50 percent of the erythrocytes have been hemolyzed. 21
The main treatment for G6PD deficiency is avoidance of oxidative stressors. Rarely, anemia may be severe enough to warrant a blood transfusion. Splenectomy generally is not recommended. Folic acid and iron potentially are useful in hemolysis, although G6PD deficiency usually is asymptomatic and the associated hemolysis usually is short-lived. Antioxidants such as vitamin E and selenium have no proven benefit for the treatment of G6PD deficiency. 6, 31 Research is being done to identify medications that may inhibit oxidative-induced hemolysis of G6PD-deficient red blood cells. 32
Hemolytic anemia due to the ingestion of fava beans or after inhalation of pollen from the vicia fava plant by persons with glucose-6-phosphate dehydrogenase d eficient erythrocytes. Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.
D55.0 Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency. D55.1 Anemia due to other disorders of glutathione metabolism. D55.2 Anemia due to disorders of glycolytic enzymes. D55.3 Anemia due to disorders of nucleotide metabolism.
A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.