Poisoning by phenytoin ICD-10-CM T42.0X1A is grouped within Diagnostic Related Group (s) (MS-DRG v39.0): 917 Poisoning and toxic effects of drugs with mcc 918 Poisoning and toxic effects of drugs without mcc Convert T42.0X1A to ICD-9-CM
Phenytoin toxicity ICD-10-CM T42.0X5A is grouped within Diagnostic Related Group (s) (MS-DRG v38.0): 791 Prematurity with major problems 793 Full term neonate with major problems
T42.0X1A is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Short description: Poisoning by hydantoin derivatives, accidental, init The 2021 edition of ICD-10-CM T42.0X1A became effective on October 1, 2020.
ICD-9-CM Diagnosis Code E980.4 : Poisoning by other specified drugs and medicinal substances, undetermined whether accidentally or purposely inflicted Free, official info about 2015 ICD-9-CM diagnosis code E980.4.
To distinguish among poisoning, adverse effect, or underdosing by drugs, medicinal, and biological substances (T36-T50) when assigning ICD-10-CM diagnostic codes, consider the following definitions: Poisoning indicates improper use of a medication, to include overdose, wrong substance given or taken in error, or wrong route of administration.
T42.0X1APoisoning by hydantoin derivatives, accidental (unintentional), initial encounter. T42. 0X1A is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM T42.
Phenytoin toxicity is rarely fatal, but can cause neurologic symptoms ranging from nystagmus to ataxia to coma. Intravenous phenytoin administration may rarely be complicated by the Purple Glove Syndrome.
Signs and symptoms of phenytoin toxicity typically correspond to the serum level, and progress from occasional mild nystagmus at 10-20 mcg/mL (the therapeutic range) to coma and seizures at levels above 50 mcg/mL (see Presentation and Workup).
Excessive self-medication, misunderstanding of the prescription order, and probable drug interaction were the three leading causes of acute phenytoin intoxication. Unsteady gait, dizziness/vertigo, nausea/vomiting, general weakness, and drowsiness were the most common presenting symptoms.
Cases of bradycardia and cardiac arrest have been reported in DILANTIN-treated patients, both at recommended phenytoin doses and levels, and in association with phenytoin toxicity [see OVERDOSE]. Most of the reports of cardiac arrest occurred in patients with underlying cardiac disease.
Phenytoin is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.
Phenytoin blood testing is ordered because phenytoin blood levels must be maintained within a narrow therapeutic range. If levels are too low, the affected person may experience seizures; if they are too high, the person may experience symptoms associated with phenytoin toxicity.
There is no antidote, and there is no evidence that any method of gastrointestinal decontamination or enhanced elimination improves outcome.
Phenytoin therapy should be stopped in all cases, and if toxicity continues to resolve, a serum level may be reassessed in 2 to 3 days to guide resumption of therapy. Patients with significant or persistent complications following the intravenous administration of phenytoin should be admitted.
Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Phenytoin may cause swelling and bleeding of the gums.
Common side effectsHeadaches. Make sure you rest and drink plenty of fluids. ... Feeling drowsy, sleepy or dizzy. As your body gets used to phenytoin, these side effects should wear off. ... Feeling nervous, unsteady or shaky. ... Feeling or being sick (nausea or vomiting) ... Constipation. ... Sore or swollen gums.
Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use. It typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb. Treatment is supportive, and most cases resolve within days to weeks.
The high-alert medications were: amiodarone, digoxin, dopamine, epinephrine, fentanyl, gentamycin, heparine, insulin, morphine, norepinephrine, phenytoin, potassium, propofol and tacrolimus.
Recovery is likely. Moderate overdose -- With proper treatment, the person usually makes a complete recovery within 24 to 48 hours. Severe overdose -- If the person is unconscious or has abnormal vital signs, more aggressive treatments may be necessary. It may take 3 to 5 days before the person becomes conscious.
Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use. It typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb. Treatment is supportive, and most cases resolve within days to weeks.
Known hypersensitivity to hydantoin products. Because of its effect on ventricular automaticity, IV phenytoin is contraindicated in sinus bradycardia, sinoatrial block, second and third-degree AV block, patients with Adams-Stokes syndrome.