icd code for factor v leiden

by Gretchen Abbott 7 min read

D68.5 Primary thrombophilia. An abnormality that refers to mutation of factor v leiden, which is a variant of human factor v. It results in thrombophilia, deep vein thrombosis, and a slightly increased risk of miscarriage. ICD-10-CM D68.51 is grouped within Diagnostic Related Group (s) (MS-DRG v36.0):

Factor v leiden mutation (r506q) is the most common cause of apc resistance
apc resistance
Activated protein C resistance (APCR) is a hypercoagulability (an increased tendency of the blood to clot) characterized by a lack of a response to activated protein C (APC), which normally helps prevent blood from clotting excessively.
https://en.wikipedia.org › wiki › Activated_protein_C_resistance
. An abnormality that refers to mutation of factor v leiden, which is a variant of human factor v. It results in thrombophilia
thrombophilia
Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).
https://en.wikipedia.org › wiki › Thrombophilia
, deep vein thrombosis, and a slightly increased risk of miscarriage.

Full Answer

What are the chances of getting Leiden factor V?

If you have the heterozygous type, there is a 50% chance that your child will inherit a Factor V Leiden gene from you. There is also a 50% chance that your child will inherit your normal Factor V gene. If you have the homozygous type, your child will inherit a Factor V Leiden gene.

Should I get tested for factor V Leiden?

Your doctor can diagnose FVL by ordering special screening and confirmatory blood tests that are specific to detect the presence of the mutation. Despite the fact that FVL can be diagnosed by simple blood tests, such testing is not necessary in every person with a personal or family history of DVT or PE.

What are the best treatments for factor V Leiden?

  • Be safe. Avoid bruises and cuts. ...
  • Stay active. Even if you've been on bed rest after surgery or for other reasons, get moving as soon as your doctor gives you the OK. ...
  • Be smart about hormones. ...
  • Wear compression stockings. ...
  • Eat a healthy, low-salt diet. ...
  • Stay at a healthy weight. ...
  • Quit smoking. ...
  • Lift up. ...

Does factor V Leiden have a cure?

What is the Treatment for Factor V Leiden ? Most people with Factor V Leiden do not form abnormal clots and require no treatment. If abnormal clots become an issue, "blood-thinning" medications, like Coumadin, can be used to impair the clotting system. This will halt growth of the clot and reduce the risk of future clots. Complications

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What is the ICD-10 code for family history of factor V Leiden?

Z83. 2 - Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism | ICD-10-CM.

What is the ICD-10 code for clotting disorder?

ICD-10 code D68. 9 for Coagulation defect, unspecified is a medical classification as listed by WHO under the range - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism .

What is factor V Leiden heterozygous?

Heterozygous means that the 2 copies of a gene are different. In your case, one of your Factor V gene codes is for normal clotting Factor V and the other Factor V gene code is for Factor V Leiden. There is more risk of a blood clot if both gene codes are for Factor V Leiden (ie in the homozygous state).

What is the factor 5 gene?

Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs.

What is the ICD 10 code for factor V deficiency?

Acquired coagulation factor deficiency D68. 4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. The 2022 edition of ICD-10-CM D68. 4 became effective on October 1, 2021.

What ICD-10 covers PT PTT?

NCD - Partial ThromboplastinTime (PTT) (190.16)

What is the difference between Factor V and Factor V Leiden?

Factor V Leiden is a common change in a gene that controls a protein called Factor V. Factor V is a protein involved in blood clotting and the Factor V Leiden gene change (also called mutation) is linked to an increase risk of blood clots.

Is Factor V Leiden considered a blood disorder?

Factor V Leiden thrombophilia is an inherited disorder of blood clotting .

What are the two types of Factor V Leiden?

Having 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. Having 2 Factor V Leiden genes (homozygous type) makes the risk much greater. Having Factor V Leiden does not appear to increase the chances of developing a heart attack or stroke.

Why is it called factor V Leiden?

Pulmonary embolism occurs when pieces or fragments of a blood clot – usually from a DVT of the leg - break off and travel to the vessels in the lungs. The mutation is named factor V “Leiden” because it was originally discovered at the University of Leiden in the Netherlands, in 1994.

What is the CPT code for clotting factor V?

Group 1CodeDescription81241F5 (COAGULATION FACTOR V) (EG, HEREDITARY HYPERCOAGULABILITY) GENE ANALYSIS, LEIDEN VARIANT81291MTHFR (5,10-METHYLENETETRAHYDROFOLATE REDUCTASE) (EG, HEREDITARY HYPERCOAGULABILITY) GENE ANALYSIS, COMMON VARIANTS (EG, 677T, 1298C)1 more row

What is the difference between Factor 5 and factor 2?

The Factor V variant known as Factor V Leiden (or rs6025) is associated with an approximately 300% increased risk in heterozygotes and an up to 8000% increased risk in homozygotes. The Factor II rs1799963 polymorphism (or G20210A) may also independently increase the risk by approximately 200%.

Does factor V Leiden affect life expectancy?

We conclude that there is no major effect of APC resistance on life expectancy. Therefore, long-term anticoagulation in carriers of factor V Leiden, on the basis of the carrier state alone, is not indicated.

Which is worse Factor 5 or factor 2?

The Factor V variant known as Factor V Leiden (or rs6025) is associated with an approximately 300% increased risk in heterozygotes and an up to 8000% increased risk in homozygotes. The Factor II rs1799963 polymorphism (or G20210A) may also independently increase the risk by approximately 200%.

Is factor V Leiden homozygous rare?

Approximately 1 in 25 people are born with one Factor V Leiden gene, and around 1 in 2,500 are born with two.

What should you avoid with factor V Leiden?

If your factor V Leiden requires you to take anticoagulant medication, here are some steps that might help you prevent injury and avoid excessive bleeding:Avoid playing contact sports or engaging in other activities that could result in physical injury. ... Use a soft toothbrush and waxed floss.More items...•

Known As

Factor V leiden is also known as activated Protein C resistance, anticardiolipin syndrome, antiphospholipid syndrome, antiphospholipid syndrome complication in pregnancy, antiphospholipid syndrome in pregnancy, antiphospholipid syndrome postpartum, antithrombin 3 deficiency, antithrombin III deficiency, factor 5 Leiden mutation, factor 5 Leiden mutation heterozygous, factor 5 Leiden mutation homozygous, factor V Leiden mutation, factor V Leiden mutation heterozygous, factor V Leiden mutation homozygous, hereditary antithrombin III deficiency, hereditary heparin cofactor II deficiency, hereditary protein C deficiency, hereditary protein S deficiency, hereditary thrombophilia, heterozygous Factor V Leiden mutation, heterozygous protein C deficiency, heterozygous protein S deficiency, heterozygous prothrombin G20210A mutation, homozygous Factor V Leiden mutation, homozygous protein C deficiency, homozygous protein S deficiency, homozygous prothrombin G20210A mutation, hypercoagulability state, hypercoagulable state, hypercoagulable state (tendency to form clots), hypercoagulable state primary, lupus anticoagulant, lupus anticoagulant disorder, postpartum (after childbirth) antiphospholipid syndrome, postpartum antiphospholipid syndrome, protein C deficiency disease, protein C deficiency disorder, protein C resistance, protein S deficiency disease, protein S deficiency disorder, prothrombin G20210A mutation, prothrombin gene mutation, resistance to activated protein C due to Factor V Leiden, thrombophilia due to acquired antithrombin III deficiency, thrombophilia due to acquired protein C deficiency, thrombophilia due to acquired protein S deficiency, thrombophilia due to antiphospholipid antibody, and upper gastrointestinal hemorrhage associated with hypercoagulability state.

Factor V Leiden Definition and Symptoms

Factor V leiden is a mutation in the clotting factor V in the blood. This mutation greatly increases a persons chance of developing blood clots in veins. Men and women are equally affected by this mutation.

What is the name of the deficiency of fibrinogen in the blood?

A blood coagulation disorder characterized by the complete absence of fibrinogen in the blood, resulting in bleeding. A deficiency of blood coagulation factor v (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as owren's disease or parahemophilia.

What is a blood coagulation disorder?

A usually inherited blood coagulation disorder characterized by the partial or complete absence of fibrinogen in the blood, resulting in bleeding. A very rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor v, resulting in bleeding.

What is factor V?

In the human body, factor V is a protein that is necessary for proper blood clotting. Some people have a genetic mutation of the protein which is called factor V Leiden. This is a disorder that can cause a condition known as thrombophilia. If you have the factor V Leiden mutation, you are at greater risk of developing blood clots.

How to find out if you have factor V?

In order to find out if you have factor V Leiden, a screening can be done by taking a sample of your blood to test for activated protein C resistance. A positive result may mean that you have the factor V Leiden mutation.

Why should you be tested for factor V?

Because deep vein thrombosis and pulmonary embolism are serious enough to be life threatening, if you suspect that you have the genetic mutation of factor V, factor V Leiden, you should be tested to determine your risk factor for thrombophilia.

What insurance covers factor V?

Part A (hospital insurance) covers the cost of your Factor V Leiden screening test if your physician deems it medically necessary and orders it while you are being cared for as an inpatient or in a skilled nursing facility.

Where does factor V clotting occur?

This abnormal clotting most commonly occurs in either the deep veins of the legs (deep vein thrombosis), or in the lungs (pulmonary embolism). Not everyone who has factor V Leiden experiences abnormal clotting, but there is a higher risk for those that do.

Is factor V inherited?

Statistics indicate that factor V Leiden is the most common inherited form of thrombophilia in the United States and Europe among Caucasians. Fortunately, Medicare recipients have coverage for the necessary blood test needed to screen for this condition.

Is factor V Leiden hereditary?

Because factor V Leiden is a hereditary condition, you may have an increased chance of having it if you have a relative with factor V Leiden. It is also more common for Caucasians of European descent to have this factor V mutation. In order to find out if you have factor V Leiden, a screening can be done by taking a sample ...

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