ICD-10 code Z51. 81 for Encounter for therapeutic drug level monitoring is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .
Medication Management ICD-10-PCS GZ3ZZZZ is a specific/billable code that can be used to indicate a procedure.
When a person takes a dose of vancomycin, the amount in the blood rises for a period of time, peaks, and then begins to fall, usually reaching its lowest level, or trough, just before the next dose. The next dose is timed to coincide with the falling concentration of the drug in the blood.
Trough: just before 4th dose of a new regimen (prior to 3rd dose for dosing intervals ≥ 24 hours or changing renal function) - Trough levels should be obtained within 30 minutes before the next scheduled dose. - Weekly vancomycin levels should be obtained for long-term vancomycin use with stable renal function. i.
Other specified counselingICD-10 code Z71. 89 for Other specified counseling is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .
2022 ICD-10-CM Diagnosis Code Z79. 899: Other long term (current) drug therapy.
Peak–trough vancomycin dosing is designed to achieve a C peak of 20–40 mg/L and a C trough of 10–15 or 15–20 mg/L, depending on the severity of the infection and the nature of the pathogen. New treatment guidelines for vancomycin suggest that therapy should achieve an AUC 24/MIC of ≥400.
In medicine and pharmacology, a trough level or trough concentration (Ctrough) is the concentration reached by a drug immediately before the next dose is administered, often used in therapeutic drug monitoring.
Trough concentrations are recommended for therapeutic monitoring of vancomycin, preferably acquired at steady-state (just before fourth dose). To avoid development of resistance, vancomycin trough levels should remain above 10.0 mcg/mL. Complicated infections require higher target levels, typically 15.0 to 20.0 mcg/mL.
A peak is the highest level of a medication in the blood, while a trough level indicates the lowest concentration. Troughs of medication concentration occur after the drug has been broken down and metabolized by the body.
Desired Trough Level (mg/L) hours if normal renal function, prior to 4th dose if q12h, or prior to 5th dose if q8h.) o Vancomycin clearance is enhanced in obesity. For morbidly obese patients, consider drawing first level sooner (e.g. before 2nd or 3rd dose).
The trough level is the lowest concentration in the patient's bloodstream, therefore, the specimen should be collected just prior to administration of the drug. The peak level is the highest concentration of a drug in the patient's bloodstream.
Blood typing is a screening test to determine blood groups and Rh antigen for blood transfusion and pregnancy. The four blood groups A, B, O, and AB are determined by the presence of antigens A and B or their absence (O) on a patient's red blood cells. In addition to ABO grouping, most immunohematology testing includes evaluation of Rh typing tests for Rh (D) antigen. Blood cells that express Rh (D) antigen are Rh positive. Red blood cells found lacking Rh (D) are considered Rh negative. Rh typing is also important during pregnancy because of the potential for mother and fetus Rh incompatiblity. If the mother is Rh negative but the father is Rh positive, the fetus may be positive for the Rh antigen. As a result, the mother’s body could develop antibodies against the Rh antigen. These antibodies may cross the placenta and cause destruction of the baby’s red blood cells, resulting in a condition known as hemolytic disease of the fetus and newborn.
Transfusion of blood components of the correct blood type is necessary in order to prevent an adverse immunologic reaction. These reactions can range from very mild and sub-clinical to very severe or fatal, depending upon the components involved and condition of the recipient.
Vancomycin, Trough - Vancomycin is an antibiotic used in the treatment of bacterial infections, especially methicillin-resistant staphylococci.
Plasma collected in: EDTA (lavender-top) tube, sodium heparin (green-top) tube, lithium heparin (green-top) tube, 3.2% sodium citrate (light blue-top) tube, or fluoride/oxalate (gray-top) tube