Transient acantholytic dermatosis is a self-limited, primary acantholytic disease that occurs predominantly in persons over 50 years old. The primary lesions, discrete papules and papulovesicles, are distributed mainly on the chest, back, and thighs and may be intensely pruritic.
Grover's disease is a rare, transient skin disorder that consists of small, firm, raised red lesions, most often on the skin of the chest and back. Diagnosis of this disorder becomes apparent under microscopic examination when the loss of the “cement” that holds the skin cells together is observed.
The current treatment options include avoidance of exacerbating factors, topical agents (eg, corticosteroids, calcineurin inhibitors, vitamin D analogs), and oral antihistamines. Oral retinoids, methotrexate, and psoralen and ultraviolet A have been used in recalcitrant cases, with various degrees of success.
Acantholytic dyskeratosis is a histopathologic pattern defined by a hyperkeratotic and parakeratotic epidermis with intraepidermal clefts containing acantholytic and dyskeratotic keratinocytes.
1 for Transient acantholytic dermatosis [Grover] is a medical classification as listed by WHO under the range - Diseases of the skin and subcutaneous tissue .
What causes transient acantholytic dermatosis? The cause of transient acantholytic dermatosis is unknown. Due to the frequent association with skin occlusion, heat, and sweating, one theory suggests Grover disease is due to sweat duct damage and occlusion.
Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders.
It causes sudden red, raised, blistery, and sometimes very itchy spots that form around the middle of the body. The rash is most often seen in middle-aged men. Another name for this condition is transient acantholytic dermatosis (TAD).
Grover's disease (GD) is a transient or persistent, monomorphous, papulovesicular, asymptomatic or pruritic eruption classified as non-familial acantholytic disorder. Contribution of autoimmune mechanisms to GD pathogenesis remains controversial.
Acantholytic dyskeratotic acanthoma: a variant of a benign keratosis.
Adenoid (acantholytic) squamous cell carcinoma (ASCC) is a histological variant of squamous cell carcinoma which occurs mainly in the sun-exposed areas of the head and neck region. It is commonly seen among males which mainly occurs in the sixth and seventh decade of life with lip being predominately affected.
Its cause remains obscure, but hospitalized, febrile and sun-damaged patients are particularly prone. It is frequently associated with some other skin diseases, including eczemas, psoriasis and solar keratoses.
Treating Grover's disease Your dermatologist will prescribe you a cortisone cream. Larger outbreaks that itch and cover the entire trunk can typically be treated using oral medication. Your dermatologist may prescribe the antibiotic tetracycline or Accutane, a popular acne treatment drug, for one to three months.
For people who have more persistent cases associated with sun-damaged or dry skin, symptoms of Grover's disease tend to come and go. In these individuals, the disease may flare when they are exposed to exacerbating factors such as high temperatures, sweating, or very dry skin.
Grover's disease usually begins as small itchy red bumps on the back and chest, which may then spread to the upper limbs. The bumps are usually slightly raised but can feel soft or hard to the touch. Water-filled blisters may appear alongside or inside these bumps.
Grover's disease is not a skin manifestation associated with any type of internal disease such as diabetes, cancer, or kidney disease.
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code (s). The following references for the code L11.1 are found in the index:
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code L11.1 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
Your skin is your body's largest organ. It covers and protects your body. Your skin
Grover's disease (GD), also known as benign papular acantholytic dermatosis, transient acantholytic dermatosis, and persistent acantholytic dermatosis is a polymorphic, pruritic, papulovesicular dermatosis characterized histologically by acantholysis:529 with or without dyskeratosis.
This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code L11.1 and a single ICD9 code, 702.8 is an approximate match for comparison and conversion purposes.