A CCP antibody test is used to help diagnose rheumatoid arthritis. It's often done along with or after a rheumatoid factor (RF) test. Rheumatoid factors are another type of autoantibody. RF tests used to be the main test to help diagnose rheumatoid arthritis.Jul 30, 2020
M05.9Rheumatoid arthritis with rheumatoid factor, unspecified M05. 9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
Anti-CCP antibodies are better than rheumatoid factor for diagnosing rheumatoid arthritis. Serum concentrations of antibodies against cyclic citrullinated peptide (anti-CCP) seem to be just as sensitive and more specific than rheumatoid factor for diagnosing rheumatoid arthritis and predicting its progression.Jun 14, 2007
Cyclic Citrullinated Peptide (CCP) Antibody, IgG/IgA (LAB001584)Performed:Twice a week on Wednesdays and FridaysLab:Antiphospholipid Standardizatin Laboratory CLIA 45D107321Synonyms:Anti CCP, Anti-CCP, anti-Cyclic Citrullinated Peptide (CCP) Antibody, IgG/IgACPT 4 Code:8620013 more rows
ICD-Code M81. 0 is a billable ICD-10 code used for healthcare diagnosis reimbursement of Age-Related Osteoporosis without Current Pathological Fracture. Its corresponding ICD-9 code is 733.
M06.9Rheumatoid arthritis, unspecified M06. 9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
CCPAcronymDefinitionCCPChinese Communist PartyCCPCertified Compensation ProfessionalCCPCenter for Communication ProgramsCCPCommunity College of Philadelphia232 more rows
The normal level of anti-CCP is less than 20 Units. (At Hospital for Special Surgery, anti-CCP is reported in Units. Some labs report this same result using a different measurement notation, that is, as less than 20 EU/ml.) A level above 20 suggests the possibility of RA.Apr 20, 2015
A CCP antibody test requires a blood sample. This test is used to help diagnose or rule out rheumatoid arthritis and to assess its potential severity. Rheumatoid arthritis is an autoimmune disorder in which the body attacks healthy cells in a person's joints.Nov 9, 2021
With a specificity of about 96% and a positive likelihood ratio of about 14, anti-CCP assists with the diagnosis of RA. It is present in only a quarter to half of patients before or at diagnosis, so a negative result does not rule out RA. It can also predict aggressive joint erosion.
Under ICD10, M05 and M06 diagnosis codes are reasonable proxies to identify seropositive and seronegative RA with high sensitivity and positive predictive values if lab test results are not available.
In summary, the use of the M05 and M06 ICD10 diagnosis codes appears reasonably useful to identify RA patients with seropositive or seronegative disease, a finding that likely will facilitate clinical research in data systems where lab results are not available. Similar to the fashion in which some EMR vendor systems assign obesity ICD-10 diagnosis codes automatically based on the calculated body mass index, EMR vendors could consider assigning the appropriate M05/M06 RA diagnosis code based on RF and/or anti-CCP lab test results to further improve the accuracy and utility of using structured data (i.e., diagnosis codes) in settings where lab results might not be available.
The shift in the USA from the International Classification of Diseases, 9th edition (ICD-9), to the 10th edition (ICD-10) that occurred in October of 2015 greatly increased the number of diagnostic codes available to classify patient’s medical condition.
Because RF and anti-CCP lab test results initially might be negative in early RA and subsequently become positive on repeat testing, if a patient had more than one RF or anti-CCP lab test result, it was classified as positive if any of them were positive, up to the date of the 2nd M05/M06 diagnosis code.
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.