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Is Charcot Marie Tooth a serious disease?

Complications of Charcot-Marie-Tooth disease vary in severity from person to person. Foot abnormalities and difficulty walking are usually the most serious problems. Muscles may get weaker, and you may injure areas of the body that experience decreased sensation.

What is the prognosis for Charcot Marie Tooth?

Charcot-Marie-Tooth disorder affects one in 2,500 Australians The debilitating ... But it was not until she reached her 40s that a diagnosis made her realise what she had experienced her entire life. "I remember my dad had funny feet," Mrs Foster said. "

How does Charcot Marie Tooth effect the body?

Other tests used to diagnose Charcot-Marie-Tooth (CMT) disease include:

• Ultrasound
• Magnetic resonance imaging ( MRI) of lower limb muscles
• Electromyography ( EMG)
• Nerve conduction studies
• Nerve biopsy (rarely used)

How to diagnose Charcot Marie Tooth?

There's no cure for CMT, but braces, physical/occupational therapy, and other orthopedic devices, and even orthopedic surgery can help cope with the symptoms of the disease. Charcot-marie-tooth ...

Is Charcot foot the same as Charcot-Marie-Tooth?

Charcot foot is acquired and often caused by diabetes. Charcot-Marie-Tooth is a hereditary or inherited disorder. Both diseases can cause bony deformities and non-healing ulcers, but Charcot foot can be much more serious and requires immediate attention from a trained professional, such as a podiatrist.

Is Charcot-Marie-Tooth a neurological disease?

Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, and nearly all cases are inherited. CMT damages the body's peripheral nerves, making them unable to activate muscles or relay sensory informaton from the limbs back to the spinal cord and the brain.

What is Charcot-Marie-Tooth diagnosis?

How is Charcot-Marie-Tooth disease diagnosed? Diagnosis of CMT begins with a detailed medical history, family history, and neurological examination. A physician will look for evidence of muscle weakness in the arms, legs, hands, and feet, decreased muscle bulk, reduced tendon reflexes, and sensory loss.

Is Charcot-Marie-Tooth upper or lower motor neuron?

The main features of CMT are a combination of lower motor neuron-type motor deficits and sensory signs and symptoms, reflecting the sensory-motor neuropathy.

Is Charcot-Marie-Tooth a form of MS?

Introduction. Over the past 20 years, several reports have linked CMT with MS in individual patients. In the case of CMT1A, by far the most common form of CMT, four cases with concomitant MS have been reported. 9–11 There have also been single case reports of MS in other rare forms of CMT.

What is the cause of Charcot-Marie-Tooth disease?

What causes CMT? CMT is caused by an inherited fault in one of the many genes responsible for the development of the peripheral nerves. This fault means the nerves become damaged over time. A child with CMT may have inherited the genetic fault responsible for the condition from 1 or both of their parents.

What are the types of Charcot-Marie-Tooth disease?

Subdivisions of Charcot-Marie-Tooth DiseaseCMT1: demyelinating autosomal dominant.CMT2: axonal, autosomal dominant.CMT4: recessive.CMTX: X linked.CMTDI: dominant intermediate.CMTRI: recessive intermediate.

Is Charcot-Marie-Tooth disease an autoimmune disease?

Is Charcot-Marie-Tooth an autoimmune disease? No, CMT is not an autoimmune disease. People with CMT have problem genes (mutations) that cause degeneration of their peripheral nerves.

What is Charcot-Marie-Tooth disease type 1A?

Charcot-Marie-Tooth disease type 1A (CMT1A) is a type of inherited neurological disorder that affects the peripheral nerves. People with this disease experience weakness and wasting (atrophy) of the muscles of the lower legs beginning in adolescence; later they can also have hand weakness and sensory loss.