CPT® 81370, Under HLA Typing The Current Procedural Terminology (CPT®) code 81370 as maintained by American Medical Association, is a medical procedural code under the range - HLA Typing.
A type of molecule found on the surface of most cells in the body. Human leukocyte antigens play an important part in the body's immune response to foreign substances. They make up a person's tissue type, which varies from person to person.
Human leukocyte antigen (HLA) typing is used to match patients and donors for bone marrow or cord blood transplants. HLA are proteins -- or markers -- found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not.
How HLA testing is done. A sample of blood is taken by inserting a needle into a vein in your arm. Sometimes a swab of cells is taken from inside of your cheek (called a buccal swab) for testing. No special preparation is needed for either method.
The human leukocyte antigen (HLA) system or complex is a complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for the regulation of the immune system. The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals.
There are three general groups of HLA, they are HLA-A,HLA-B and HLA-DR. There are many different specific HLA proteins within each of these three groups.
One of the tests you will have before you go on the waiting list is HLA typing, also called tissue typing. This test identifies certain proteins in your blood called antigens. Antigens are markers on the cells in your body, which help your body, tell the difference between self and non-self.
For typing of the HLA antigens there are used cellular, serological, biochemical and DNA methods.
How does matching happen?You and potential donors will have blood drawn or will have the inside of your cheek swabbed.The blood or cheek swab is tested in a lab to figure out your HLA type.Your HLA type will be compared to potential donors to see if there is a match.
HLA (human leukocyte antigen ) typing is a kind of genetic test. HLA typing is sometimes called HLA matching. HLA typing looks at certain factors related to the immune system.
HLA class I antigens (A, B, and C in humans) render each cell recognisable as “self,” whereas HLA class II antigens (DR, DP, and DQ in humans) stimulate the immune system. Both have been implicated in the rejection of transplanted organs. Three main processes are used to perform HLA typing.
There are two methodologies for running the HLA-B27 test: a serologic test using flow cytometry (CPT 86812) and a molecular test, which uses polymerase chain reaction (PCR) based methodology (CPT 81374).
Genetic susceptibility to other disease 1 Z15.89 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 2 The 2021 edition of ICD-10-CM Z15.89 became effective on October 1, 2020. 3 This is the American ICD-10-CM version of Z15.89 - other international versions of ICD-10 Z15.89 may differ.
Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00 -Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
CPT codes, descriptions and other data only are copyright 2021 American Medical Association. All Rights Reserved. Applicable FARS/HHSARS apply.
This Billing and Coding Article provides billing and coding guidance for Local Coverage Determination (LCD) L34518 Molecular Pathology Procedures for Human Leukocyte Antigen (HLA) Typing. Please refer to the LCD for reasonable and necessary requirements.
It is the provider’s responsibility to select codes carried out to the highest level of specificity and selected from the ICD-10-CM code book appropriate to the year in which the service is rendered for the claim (s) submitted.
All those not listed under the “ICD-10 Codes that Support Medical Necessity” section of this article.
Contractors may specify Bill Types to help providers identify those Bill Types typically used to report this service. Absence of a Bill Type does not guarantee that the article does not apply to that Bill Type.
Contractors may specify Revenue Codes to help providers identify those Revenue Codes typically used to report this service. In most instances Revenue Codes are purely advisory. Unless specified in the article, services reported under other Revenue Codes are equally subject to this coverage determination.
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
HLA-B*58:01 Typing - HLA B*58:01 has been associated with severe cutaneous adverse reactions (SCAR) in response to the drug Allopurinol.
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