Phases:
The Anatomy of the Optic Nerve
The doctor will diagnose Optic Neuritis based on characteristic findings at the time of a careful examination. Some patients with optic neuritis will have mild swelling of the optic nerve and surrounding retina that is visible to the physician during examination with the ophthalmoscope.
Your ophthalmologist will check your eyes thoroughly and do the following things:
ICD-10-CM Code for Benign neoplasm of meninges, unspecified D32. 9.
Benign neoplasm of meninges, unspecified The 2022 edition of ICD-10-CM D32. 9 became effective on October 1, 2021. This is the American ICD-10-CM version of D32.
ICD-10-CM Code for Encounter for surgical aftercare following surgery on the nervous system Z48. 811.
ICD-10-CM Code for Benign neoplasm of peripheral nerves and autonomic nervous system, unspecified D36. 10.
A meningioma is a primary central nervous system (CNS) tumor. This means it begins in the brain or spinal cord. Overall, meningiomas are the most common type of primary brain tumor.
Craniotomy for Excision of Meningioma (CPT 61512) General: Patients may be symptomatic or asymptomatic.
Other specified postprocedural statesICD-10 code Z98. 890 for Other specified postprocedural states is a medical classification as listed by WHO under the range - Factors influencing health status and contact with health services .
ICD-10-CM Code for Encounter for surgical aftercare following surgery on specified body systems Z48. 81.
CPT® 61510, Under Craniectomy or Craniotomy Procedures The Current Procedural Terminology (CPT®) code 61510 as maintained by American Medical Association, is a medical procedural code under the range - Craniectomy or Craniotomy Procedures.
(nerv sheeth) The tissue that covers and protects the nerves that are outside the brain and spinal cord. The nerve sheath is made up of connective tissue and myelin (a substance that contains protein and fat).
Malignant Peripheral Nerve Sheath Tumor, or MPNST, is a cancer of the cells that form the sheath that covers and protects peripheral nerves. Peripheral nerves are those outside of the central nervous system (brain and spinal cord). MPNST is a type of sarcoma.
A schwannoma is a tumor that develops from Schwann cells in your peripheral nervous system or nerve roots. They're almost always benign and slow-growing.
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere.
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology] Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, ...
For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. Malignant neoplasm of ectopic tissue. Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, ...
Optic Nerve Sheath Meningiomas (ONSM) are uncommon, benign neoplasms originating from the meningothelial cells of the meninges surrounding the optic nerve. The tumor may arise from either the intraorbital or intracanalicular portions of the optic nerve where there is a meningeal sheath. Primary ONSM should be differentiated from secondary intracranial meningiomas that extend anteriorly to involve the optic nerve. Although considered benign tumors, primary ONSMs cause slow, progressive vision loss secondary to compression of the adjacent optic nerve and its blood supply. This monograph discusses primary ONSM.
Although rare, ONSM is the second-most common primary optic nerve tumor and represents 1-2% of all meningioma.. They account for one-third of primary optic nerve tumors. The incidence of ONSM is highest in adult women in the fourth or fifth decades of life, with women being three times more likely than men to be affected. ONSM however can rarely occur in children: a review of cases by Dutton showed that only 4% of tumors occurred in patients younger than 20 years.
The diagnosis of ONSM is clinical and then confirmed with neuroimaging. Although computed tomography (CT) of the head and orbit may show the lesion (especially if calcified), magnetic resonance imaging (MRI) of the head and orbit with gadolinium and fat suppression sequences is generally recommended for ONSM. The CT scan findings include diffuse, tubular, lesions with contrast-enhancement. Calcifications may be present within the tumor as well and are better seen on CT. MRI studies of the head and orbit with gadolinium contrast as well as fat suppression sequences are useful for identifying the involvement of the sheath and the radiographic features are usually so typical for ONSM that a biopsy may not be necessary in the appropriate clinical setting. MRI may demonstrate diffuse, tubular thickening of the optic nerve sheath encasing the optic nerve, often producing a characteristic "tram track" sign on axial cuts or a "doughnut" sign on coronal cuts. The tumor usually enhances homogenously and vigorously after contrast infusion. MRI may also be useful in delineating the extent of the tumor and for evaluating for intracranial extension. Ga-68 PET/CT has recently been considered as a diagnostic tool for the detection of meningiomas via exploitation of their somatostatin receptor ligands. Sensitivity and selectivity was found to be 10% higher in the detection of primary or recurrent meningiomas compared to MRI and has also shown high potential in its ability to predict tumor growth rate. PET scan is usually not necessary for the diagnosis of typical ONSM, however. Biopsy of the tumor is not necessary for diagnosis in typical clinical cases with characteristic radiographic features for ONSM and surgery carries a high risk of damage to the optic nerve.
Patients with ONSM may be asymptomatic. Symptomatic patients with ONSM most often present with gradually progressive, painless monocular vision loss. Visual acuity at presentation can vary considerably (20/20 to no light perception) due to variable levels of awareness of visual loss. Dutton's review found that 24% of patients had visual acuity of counting fingers or worse, while 45% of patients had visual acuity of 20/40 or better. Evidence of optic nerve dysfunction (e.g., reduced color vision, visual field loss, an ipsilateral relative afferent pupillary defect, and optic atrophy/optic disc edema) are typically present. Patients may demonstrate a classic clinical triad of ONSM: 1) painless, slowly progressive vision loss, 2) optic atrophy, and 3) so called “optociliary shunt vessels." The full triad however is seen in only a minority of cases, however. “Optociliary shunt vessels” are collateral vessels formed in response to chronic occlusion of the central retinal vein (and not a true shunt) and serve to carry blood from the retinal venous circulation to the choroidal circulation (i.e., retinochoroidal venous collateral). These retinochoroidal venous collaterals (RCVC) however are not specific for ONSM. In addition, RCVC are seen in only 30% of patients with ONSM. Patients with orbital ONSM may also have proptosis or extraocular motility deficits, depending on the location and size of the tumor. Funduscopic exam may reveal an initially normal or swollen optic disc, but eventually optic atrophy develops (with or without RCVC).
Patients with ONSM may be observed if asymptomatic and generally the clinical course and imaging are sufficient to make the diagnosis. Although the lesions are typically histologically benign, symptomatic patients could be offered treatment. The optimal timing of treatment for ONSM is unclear due to the difficulty in predicting the variable natural course of an individual tumor. One case series found a high degree of variability of the change in visual acuity from baseline for 16 patients diagnosed with ONSM whom were then followed expectantly for an average of 6.2 years There were additionally no clear variables identified which could help predict the patients' visual outcomes other than an already poor initial visual acuity.
ONSM have also been associated with neurofibromatosis type 2. The most common cytogenetic abnormality found in meningiomas is the loss of the long arm of chromosome 22, including the region containing the NF2 gene.
These retinochoroidal venous collaterals (RCVC) however are not specific for ONSM. In addition, RCVC are seen in only 30% of patients with ONSM. Patients with orbital ONSM may also have proptosis or extraocular motility deficits, depending on the location and size of the tumor.
Radiation therapy . Stereotactic fractionated radiotherapy is the preferred modality as adjuvant treatment after surgery for meningioma in general and is the preferred primary modality of treatment for meningiomas that are in close proximity to important neurovascular structures such as the optic nerve.
For tumors infiltrating the nerve, resection is limited to the exophytic part, unless the eye has no light perception, in which case the optic nerve can be transected. As an alternative to surgical resection of the tumor, a window can be created in the dura to relieve pressure on the optic nerve (OPRS 2006; 22:278).
Women who report breastfeeding for more than 6 months are at decrease d risk of meningioma (J Neurosurg 2013; 118:649). Reproductive factors such as age at menarche, age at menopause, and parity have not been found to increase risk, despite the known increase in tumor growth during pregnancy (J Neurosurg 2013; 118:649).