icd 10 code for xolair injection

by Tyrel McKenzie 8 min read

ICD-10-CM codes J45. 41, J45. 42, J45.

What is the ICD 10 code for Xolair (omalizumab)?

 · 07/01/2021. R4. Based on an FDA update, ICD-10 code J33.0 has been added effective for dates of service on or after 11/30/2020. 11/07/2019. R3. This article was converted to the new Billing and Coding Article format and the brand name, Xolair® has been removed.

What is the CPT code for Xolair monoclonal antibody?

 · Because the practice didn’t buy the Xolair, they didn’t list it on the claim form and the claim was denied. Correct coding would be 96372 X 2 units (or use two claim lines) and J2357 X 1 unit (if you don’t do buy and bill, just use a nominal amount e.g., $0.01) It is also important to have the proper associated diagnosis.

How is Xolair prescribed for moderate to severe persistent asthma?

forXOLAIR ®. omalizumab) for subcutaneous use (. SAMPLE CODING. Chronic Spontaneous Urticaria. TYPE CODE DESCRIPTION. Diagnosis: ICD-10-CM. L50.0 Allergic urticaria L50.1 Idiopathic urticaria L50.8 Other (chronic, recurrent) urticaria L50.9 Unspecified urticaria. Drug: NDC Note: Payer requirements regarding use of a 10-digit or 11-digit NDC may vary.

What is the CPT code for prophylactic injection?

 · Code Maximum Allowed Xolair (omalizumab) Moderate to Severe Asthma 150mg vials 50242-0040-62 3 vials Xolair (omalizumab) Nasal Polyps 150mg vials 50242-0040-62 4 vials Xolair (omalizumab) Chronic Urticaria 150mg vials 50242-0040-62 2 vials

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How do you code Xolair injection?

A: Medicare requires the use of CPT code 96372 –Therapeutic, prophylactic, or diagnostic injection, specify substance or drug; subcutaneous or intramuscular for the administration of biologics.

What is a Xolair shot?

Xolair is a drug that acts by binding to the IgE allergic antibody in the blood stream and hence neutralizing (blocking) its actions. The U.S. Food and Drug Administration (FDA) has approved Xolair for the treatment of patients with moderate to severe persistent asthma.

What is the HCPCS code for Xolair?

HCPCS Code for Injection, omalizumab, 5 mg J2357.

Is Xolair an injection or infusion?

XOLAIR® (omalizumab) is an infusion medication used to treat moderate to severe, persistent asthma. It is effective in patients who are six years of age or older, whose asthma symptoms have not been controlled by inhaled corticosteroids.

Does Medicare pay for Xolair injections?

Do Medicare prescription drug plans cover Xolair? Yes. 100% of Medicare prescription drug plans cover this drug.

What class of medication is Xolair?

Xolair belongs to a class of drugs called Monoclonal Antibodies, Anti-asthmatics. It is not known if Xolair is safe and effective in children younger than 6 years of age.

What is medical code J2357?

INJECTION, OMALIZUMABGroup 1CodeDescriptionJ2357INJECTION, OMALIZUMAB, 5 MG

What is CPT code J0897?

Group 1CodeDescription96372THERAPEUTIC, PROPHYLACTIC, OR DIAGNOSTIC INJECTION (SPECIFY SUBSTANCE OR DRUG); SUBCUTANEOUS OR INTRAMUSCULARJ0897INJECTION, DENOSUMAB, 1 MG

What is J code J3490?

Meloxicam Injection, for Intravenous Use (Anjeso™) HCPCS Code J3490: Billing Guidelines.

Is Xolair an allergy shot?

XOLAIR is a prescription medicine used to treat appropriate allergic asthma patients. XOLAIR is not a medicine you inhale, and it is not a corticosteroid. It is for injection, given under the skin every 2 or 4 weeks.

Is Xolair a biologic?

Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic asthma, chronic idiopathic urticaria (CIU) and nasal polyps.

Is Xolair an immunotherapy?

A recent review paper published in Current Opinion in Allergy and Clinical Immunology suggests that when combined with allergen immunotherapy the biologic omalizumab (Xolair) can enhance efficacy and decrease adverse reactions.

Policy

Dosage and Administration

  • Omalizumab is available as Xolair for injection as 75 mg/0.5 mL and 150 mg/mL solution in a single-dose prefilled syringe, and 150 mg lyophilized powder in a single-dose vial for reconstitution.
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Experimental and Investigational

  1. Aetna considers the use of omalizumab with mepolizumab (Nucala) or reslizumab (Cinqair) experimental and investigational because the safety and effectiveness of these combinations has not been esta...
  2. Aetna considers measurement of fractional exhaled nitric oxide (FeNO) in predicting response to omalizumab in asthma experimental and investigational because the effectiveness of this …
  1. Aetna considers the use of omalizumab with mepolizumab (Nucala) or reslizumab (Cinqair) experimental and investigational because the safety and effectiveness of these combinations has not been esta...
  2. Aetna considers measurement of fractional exhaled nitric oxide (FeNO) in predicting response to omalizumab in asthma experimental and investigational because the effectiveness of this approach has...
  3. Aetna considers the use of omalizumab experimental and investigational for all other indications, including the following (not an all-inclusive list) because omalizumab's safety and effectiveness f...

Background

  • U.S. Food and Drug Administration (FDA)-Approved Indications
    1. Xolair is indicated for patients 6 years of age and older with moderate to severe persistent asthma who have a positive skin test or in vitro reactivity to a perennial aeroallergen and whose symptoms are inadequately controlled with inhaled corticosteroids. Limitations of use: Xolair is …
  • Compendial Uses
    1. Immune checkpoint inhibitor-related toxicities 2. Systemic mastocytosis Omalizumab is available as Xolair (Genentech, Inc.), which is a recombinant DNA-derived humanized IgG1k monoclonal antibody that selectively binds to human immunoglobulin E (IgE). Omalizumab inhib…
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Appendix

  • Appendix A: Grading of Pruritis
    1. G1: Mild or localized 2. G2: Moderate. Intense or widespread; intermittent; skin changes from scratching (e.g., edema, papulation, excoriations, lichenification, oozing/crusts); limiting iADLs 3. G3: Severe. Intense or widespread; constant; limiting self-care ADLs or sleep Source: NCCN, 2021
  • Appendix B: 2017 WHO Diagnostic Criteria for Systemic Mastocytosis
    1. Major Criteria: multifocal, dense infiltrates of mast cells (at least 15 mast cells in aggregates) detected in sections of bone marrow and/or other extracutaneous organs 2. Minor Criteria 2.1. In biopsy sections of bone marrow or other extracutaneous organs, greater than 25% of mast cells …
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