Fluzone High-Dose Quadrivalent is the only licensed high-dose inactivated influenza (flu) vaccine; it is manufactured by Sanofi Pasteur Inc. Fluzone High-Dose Quadrivalent is a four-component (quadrivalent) flu vaccine approved for people 65 years and older.
The ICD-10 code to use for flu vaccination is Z23, encounter for immunization. There are many CPT codes to describe influenza vaccine, varying by manufacturer, product and age group.
For 2021-2022, there are two influenza vaccines that are specifically approved for people aged 65 and older: Fluzone High-Dose Quadrivalent: This vaccine contains four times the amount of antigen, compared to Fluzone standard-dose. It is approved for adults age 65+.
G0008 administration of influenza virus vaccine.
ICD-10 requires only one code (Z23) per vaccination, regardless if single or combination. Report Z23 for all vaccination diagnoses.
ICD-10-CM Code for Encounter for immunization Z23.
The high dose vaccine (brand name Fluzone High-Dose) contains four times the amount of antigen (the inactivated virus that promotes a protective immune response) as a regular flu shot. It is associated with a stronger immune response following vaccination (higher antibody production).
In response to a regular flu shot, older people produce 50% to 75% fewer antibodies, which protect against the vaccine antigens, than do younger adults. Studies have found higher antibody levels in older adults who received high-dose flu vaccines than in those who received standard-dose flu vaccines.
Adjuvanted quadrivalent flu vaccine is approved for people 65 years and older. It is manufactured using an egg-based process (like most flu vaccines), and includes an adjuvant called MF59. An adjuvant is an ingredient added to a vaccine that helps create a stronger immune response to vaccination.
90471 One vaccine, single or combination vaccine/toxoid. Immunization administration (includes percutaneous, intradermal, subcutaneous or intramuscular injections).
For vaccines given the same day as a G-Code vaccine, use 90471. For example, if a patient receives a flu shot and tetanus shot, you would bill G0008 for the flu vaccine and 90471 for the tetanus vaccine; also add modifier 59 (distinct procedural service) to the G code.
You can charge your patient for the cost of the influenza vaccine. You can't bill Medicare for the vaccine itself.